Dissolution rates of various brands of proton pump inhibitors in combination with domperidone: an in vitro study
Shibendu Ghosh,
Sandip Kumar Das,
Krishna C. V.
et al.
Abstract:Background: Drug solubility, bioavailability, and dissolution rates are important in establishing in vivo efficacy. Eight brands of domperidone proton pump inhibitor combination drugs were compared to enable physicians to take an informed decision regarding the dissolution rates of various domperidone-PPI combinations available in the Indian market to allow identification and prescription of the drug with better bioavailability.
Methods: The in vitro dissolution rate of a combination of domperidone-PPI drugs w… Show more
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