Dissolution kinetics and biodurability of tremolite particles in mimicked lung fluids: Effect of citrate and oxalate

Rozalén, Marisa; Ramos, M. Elena; Huertas, F. Javier; Fiore, Saverio; Gervilla, Fernando

doi:10.1016/j.jseaes.2013.04.008

Cited by 23 publications

(21 citation statements)

References 28 publications

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“…For all the fibres, the estimated lifetime t of a fibre was determined using the equation ( 4 ) 23 , 25 : where d = fibre diameter (m): a diameter of 0.25 µm (0.25 × 10 −6 m) was assumed for the calculation; V = molar volume (m 3 ·mol −1 ), R = apparent dissolution rate normalized to the surface area (see above).…”

Section: Methodsmentioning

confidence: 99%

“…Regarding in vitro acellular dissolution studies, earlier works 23 , 24 demonstrated that chrysotile dissolves faster than anthophyllite and tremolite asbestos, along the entire pH scale (R = dissolution rate, R chr > R ant >> R trm ).…”

Section: Introductionmentioning

confidence: 99%

“…Rozalen et al . 23 measured the dissolution of tremolite at 37 °C using simulated macrophages (pH 4) and interstitial fluids (pH 7.4).…”

Section: Introductionmentioning

confidence: 99%

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In vitro acellular dissolution of mineral fibres: A comparative study

Gualtieri

Pollastri

Gandolfi

et al. 2018

Sci Rep

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The study of the mechanisms by which mineral fibres promote adverse effects in both animals and humans is a hot topic of multidisciplinary research with many aspects that still need to be elucidated. Besides length and diameter, a key parameter that determines the toxicity/pathogenicity of a fibre is biopersistence, one component of which is biodurability. In this paper, biodurability of mineral fibres of social and economic importance (chrysotile, amphibole asbestos and fibrous erionite) has been determined for the first time in a systematic comparative way from in vitro acellular dissolution experiments. Dissolution was possible using the Gamble solution as simulated lung fluid (pH = 4 and at body temperature) so to reproduce the macrophage phagolysosome environment. The investigated mineral fibres display very different dissolution rates. For a 0.25 μm thick fibre, the calculated dissolution time of chrysotile is in the range 94–177 days, very short if compared to that of amphibole fibres (49–245 years), and fibrous erionite (181 years). Diffraction and SEM data on the dissolution products evidence that chrysotile rapidly undergoes amorphization with the formation of a nanophasic silica-rich fibrous metastable pseudomorph as first dissolution step whereas amphibole asbestos and fibrous erionite show minor signs of dissolution even after 9–12 months.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In vitro acellular dissolution of mineral fibres: A comparative study

Gualtieri

Pollastri

Gandolfi

et al. 2018

Sci Rep

View full text Add to dashboard Cite

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“…A limited number of studies have investigated the dissolution rates of other amphiboles including anthophyllite (Mast and Drever, 1987 at 22°C;Chen and Brantley, 1998) and tremolite (Schott et al, 1981;Rozalen et al, 2013). No previous study, however, has reported the dissolution rates of actinolite, the amphibole present in the metabasalt considered in this work.…”

Section: Comparison Of Retrieved Actinolite and Chlorite Rates With Pmentioning

confidence: 96%

Dissolution rates of actinolite and chlorite from a whole-rock experimental study of metabasalt dissolution from 2 ≤ pH ≤ 12 at 25 °C

et al. 2014

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“…its biodurability) may be a critical determinant in its toxicity (Addison and McConnell, 2008). This connection has motivated several previous studies aimed at quantifying tremolite biodurability (Oze and Solt, 2010;Rozalen et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

An experimental study of tremolite dissolution rates as a function of pH and temperature: Implications for tremolite toxicity and its use in carbon storage

2014

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Steady-state tremolite dissolution rates, at far-from-equilibrium conditions, were measured as a function of aqueous silica and magnesium activity, pH from 1.9 to 6.7, and temperature from 25 to 150ºC. Calcium is released from tremolite faster than either Mg or Si throughout most of the experiments even after these latter elements attained steady-state release rates. The preferential removal of Ca releases fine Mg-Si rich needle-like fibres from the tremolite, probably promoting its toxicity. In contrast, Mg was released in stoichiometric or near to stoichiometric proportion to Si once steady-state was attained. Measured steady-state tremolite dissolution rates based on Si release can be described usingwhere r + signifies the BET surface area-normalized forward tremolite steady-state dissolution rate, A A refers to a pre-exponential factor = 6610 À3 mol cm À2 s À1 , E A designates an activation energy equal to 80 kJ mol À1 , R represents the gas constant, T denotes absolute temperature, and a i refers to the activity of the subscripted aqueous species. This rate expression is consistent with tremolite dissolution rates at acidic pH being controlled by the detachment of partially liberated silica tetrahedra formed from the exchange of Mg 2+ for two protons near the mineral surface after the near-surface Ca has been removed. Nevertheless, Mg release rates from tremolite are~3 orders of magnitude slower than those from forsterite and enstatite suggesting that tremolite carbonation will be far less efficient than the carbonation of these other Mg-silicate minerals.

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Dissolution kinetics and biodurability of tremolite particles in mimicked lung fluids: Effect of citrate and oxalate

Cited by 23 publications

References 28 publications

In vitro acellular dissolution of mineral fibres: A comparative study

In vitro acellular dissolution of mineral fibres: A comparative study

Dissolution rates of actinolite and chlorite from a whole-rock experimental study of metabasalt dissolution from 2 ≤ pH ≤ 12 at 25 °C

An experimental study of tremolite dissolution rates as a function of pH and temperature: Implications for tremolite toxicity and its use in carbon storage

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