Dissociation of hormonal and antigenic activity of luteinizing hormone excreted in endometrial carcinoma patients (endogenous anahormones)

Dil'man, V. M.; Golubev, V. N.; Krylova, N V

doi:10.1016/0002-9378(73)90675-3

Cited by 6 publications

(1 citation statement)

References 14 publications

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“…The hormone secreted by the tumor may be identical to the host-produced hormone, or it may vary by being more immunologically potent and less bio!ogically active, or it may resemble other intermediate substances not fully identified. 12 Thrse hormones have been called analogue hormones or parahormones (TABLE 2).…”

Section: Progenitor Cryptocides As a Producer Of An Anahormone Or Parmentioning

confidence: 99%

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF *PROGENITOR CRYPTOCIDES**

Livingston

Livingston²

1974

Trans NY Acad Sci

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Guinea pigs became skin‐positive to test doses of PPD (purified protein derivative‐Seibert) and to other related PPD preparations in various degrees following immunization with phenolized cultures of Progenitor cryptocides, an intermittently acid‐fast pleomorphic filterable Actinomycete isolated from human cancer patients. This reactivity, indicative of the relationship to M. tuberculosis as well as to several other related microbes, may account for the effective treatment of some types of human cancer with BCG (Bacillus Calmette Guérin). Another property of P. cryptocides is the production in vitro of a parahormone immunologically and biologically related to human chorionic gonadotropin. Since the cancer patient often exhibits various types of hormonal imbalance, the microbic exogenous production of this hormone may explain the neoplastic parahormone syndrome in man. There are some biological differences in experimental animals between the microbic and human chorionic gonadotropin, but the in vitro and radioimmunological tests are identical. The microbic hormone appears to play an important role in human cancer, since it not only is present in tumors, body tissues, and fluids but may be excreted in large amounts in the urine. The amount excreted is variable, depending upon the rate of microbic production of the hormone in vivo and the resistance of the host as expressed through immunological and metabolic degradation systems.

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Section: Progenitor Cryptocides As a Producer Of An Anahormone Or Parmentioning

confidence: 99%

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF *PROGENITOR CRYPTOCIDES**

Livingston

Livingston²

1974

Trans NY Acad Sci

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Prolactin in Postmenopausal Endometrial Hyperplasia and Adenocarcinoma

Volpe¹,

Pellegri²,

Boselli³

et al. 1980

The Menopause and Postmenopause

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Increased bioactive luteinizing hormone levels in postmenopausal women with endometrial cancer

Nagamani

Doherty

Smith

et al. 1992

American Journal of Obstetrics and Gynecology

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Dissociation of hormonal and antigenic activity of luteinizing hormone excreted in endometrial carcinoma patients (endogenous anahormones)

Cited by 6 publications

References 14 publications

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF *PROGENITOR CRYPTOCIDES**

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF *PROGENITOR CRYPTOCIDES**

Prolactin in Postmenopausal Endometrial Hyperplasia and Adenocarcinoma

Increased bioactive luteinizing hormone levels in postmenopausal women with endometrial cancer

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Dissociation of hormonal and antigenic activity of luteinizing hormone excreted in endometrial carcinoma patients (endogenous anahormones)

Cited by 6 publications

References 14 publications

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF PROGENITOR CRYPTOCIDES*

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF PROGENITOR CRYPTOCIDES*

Prolactin in Postmenopausal Endometrial Hyperplasia and Adenocarcinoma

Increased bioactive luteinizing hormone levels in postmenopausal women with endometrial cancer

Contact Info

Product

Resources

About

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF *PROGENITOR CRYPTOCIDES**

SOME CULTURAL, IMMUNOLOGICAL, AND BIOCHEMICAL PROPERTIES OF *PROGENITOR CRYPTOCIDES**