1979
DOI: 10.1016/0006-8993(79)90582-1
|View full text |Cite
|
Sign up to set email alerts
|

Dissociation of active from immobility components of sexual behavior in female rats by central 6-hydroxydopamine: Implications for CA involvement in sexual behavior and sensorimotor responsiveness

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

2
24
0

Year Published

1982
1982
2008
2008

Publication Types

Select...
4
3
2

Relationship

0
9

Authors

Journals

citations
Cited by 78 publications
(26 citation statements)
references
References 36 publications
2
24
0
Order By: Relevance
“…Similarly, more tyrosine hydroxylase immunoreactive cells were observed in VTA sections from E 2 +P- compared to E 2 -primed rats [48]. Following 6-hydroxydopamine lesions, there is an overcompensation in functioning of the remaining dopamine cells [49] and, among rats that received 6-OHDA lesions of the VTA, there is an exaggerated response to the facilitating effects of P on lordosis of E 2 -primed rats [50,51,52]. These findings suggest that P may have actions to increase tyrosine hydroxylase and dopamine within the VTA.…”
Section: Discussionmentioning
confidence: 99%
“…Similarly, more tyrosine hydroxylase immunoreactive cells were observed in VTA sections from E 2 +P- compared to E 2 -primed rats [48]. Following 6-hydroxydopamine lesions, there is an overcompensation in functioning of the remaining dopamine cells [49] and, among rats that received 6-OHDA lesions of the VTA, there is an exaggerated response to the facilitating effects of P on lordosis of E 2 -primed rats [50,51,52]. These findings suggest that P may have actions to increase tyrosine hydroxylase and dopamine within the VTA.…”
Section: Discussionmentioning
confidence: 99%
“…Dopamine has also been proposed to exert inhibition on lordosis based on the results of studies which used peripheral administration of dopamine receptor agonists, antagonists and synthesis inhibitors [11,12,14]. Norepinephrine containing nerve endings may also partici pate in the control of lordosis since lesions of norepineph rine cell bodies facilitate [4,17] or inhibit [15] lordosis re sponding. Particular nuclei within the hypothalamus which may mediate the effect of pargyline on behavior cannot be deter mined from the results presented here.…”
Section: Discussionmentioning
confidence: 99%
“…Such studies indicate that serotonin and dopamine may ex ert inhibitory influences on lordosis [1, 11-14, 25, 33, 35]. Noradrenergic influences on lordosis behavior may be more complex than those of the other amines since conflicts Received: June 11, 1981 Accepted after revision: September 17,1981 exist between results obtained by both pharmacological [12,33,35] and lesion techniques [4,15,17], While considerable progress has been made in describ ing the neural basis of endocrine events, current pharmaco logical studies leave unanswered the questions of whether identified hormone-sensitive monoaminergic projection sites in the hypothalamus are responsible for changes in neuroendocrine function after peripheral drug treatment and which projection sites participate in particular aspects of gonadal hormone mediation of neuroendocrine events. One approach to answering these questions would be to perturb pharmacologically specific monoaminergic, hor mone-sensitive hypothalamic sites and ascertain the effect on neuroendocrine events.…”
mentioning
confidence: 99%
“…Cag giula and colleagues (180,181) found that intraventricular administration of 6-hydroxydopamine (6-0HDA) to rats primed with estrogen increased sexual receptivity, as measured by the lordosis quotient score, but not soliciting behavior. In animals made receptive with E2 + P, intraventricular .…”
Section: Dopamine: Ovulation and Feminine Sexual Behaviormentioning
confidence: 99%