Dissociation between upper and lower neck N13 potentials following paired median nerve stimuli

Araki, Atsushi; Yamada, Thoru; Ito, Takashi; Urushibara, Nobuo; Kohira, Ryutaro; Hsu, Shih‐Pin; Yeh, Malcolm

doi:10.1016/s0168-5597(96)96045-1

Cited by 24 publications

(9 citation statements)

References 28 publications

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“…Similar results were reported by Klostermann et al (2000) with intrathalamic recordings at ISIs of 10 and 20 ms, and by Araki et al (1997) with upper cervical recordings. HFOs recorded from intrathalamic electrodes in PD patients completely recovered at an ISI of 20 ms, whereas HFOs recorded in the scalp recovered only 53% (Klostermann et al 2000).…”

Section: Interactions Between Two Consecutive Afferent Volleys Elicitsupporting

confidence: 89%

“…At an ISI of 20 ms the N20 component shows an amplitude decrease of Յ50% and recovers at ISIs of Ͼ100 ms (Frasson et al 2001;Mochizuki et al 2003). The mechanisms involved in this modulation at the dorsal column leminiscus medialis system (P14, N20) are thought to depend on the postsynaptic potentials probably mediated by interneurons within the ventroposterolateral (VPL) nucleus (Araki et al 1997;Frasson et al 2001). However, at very short ISIs (Ͻ10 ms) N20 is not identified, whereas P30 is recognized following the second stimulus (Hoshiyama and Kakigi 2002).…”

Section: Interactions Between Two Consecutive Afferent Volleys Elicitmentioning

confidence: 99%

See 1 more Smart Citation

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Costa¹,

Valls‐Solé²,

Valldeoriola³

et al. 2008

Journal of Neurophysiology

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Costa J, Valls-Solé J, Valldeoriola F, Rumià J. Subcortical interactions between somatosensory stimuli of different modalities and their temporal profile. J Neurophysiol 100: 1610 -1621, 2008. First published July 2, 2008 doi:10.1152/jn.90412.2008. Interactions between inputs of different sensory modality occur along the sensory pathway, including the thalamus. However, the temporal profile of such interaction has not been fully studied. In eight patients who had been implanted an intrathalamic electrode for deep brain stimulation as symptomatic treatment of tremor, we investigated the interactions between mechanical taps and electrical nerve stimuli. Somatosensory evoked potentials (SEPs) were recorded from Erb's point, cervical spinal cord, nucleus ventrointermedialis of the thalamus, and parietal cortex. A handheld electronic reflex hammer was used to deliver a mechanical tap to the skin overlying the first dorsal interosseous muscle and to trigger an ipsilateral digital median nerve electrical stimulus time-locked to the mechanical tap with a variable delay of 0 to 50 ms. There were significant time-dependent interactions between the two sensory volleys at the subcortical level. Thalamic SEPs were decreased in amplitude at interstimulus intervals (ISIs) from 10 to 40 ms with maximum effect at 20 ms (Ϫ42.8 Ϯ 10.5%; P Ͻ 0.001). A similar decrease was also seen in the number and frequency of the high-frequency components of thalamic SEPs (Ϫ25 Ϯ 4%). A smaller reduction (Ϫ18.1 Ϯ 5.8%; P Ͻ 0.001) was present in upper cervical response at ISI ϭ 20 ms. There were no changes in peripheral responses. Cortical SEPs were almost completely absent in some subjects at ISIs from 20 to 50 ms. There were no changes in SEP latencies. Our results indicate that significant time-dependent interactions between sensory volleys occur at the subcortical level. These observations provide further insight into the physiological mechanisms underlying afferent gating between sensory volleys of different modality.

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Section: Interactions Between Two Consecutive Afferent Volleys Elicitsupporting

confidence: 89%

Section: Interactions Between Two Consecutive Afferent Volleys Elicitmentioning

confidence: 99%

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Costa¹,

Valls‐Solé²,

Valldeoriola³

et al. 2008

Journal of Neurophysiology

View full text Add to dashboard Cite

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“…Ag-AgCl surface cup electrodes were placed on several points including NC (noncephalic reference on the contralateral shoulder), CS2 (second cervical spine), Fz (midline frontal), and CPc (centroparietal electrodes contralateral to the median nerve stimulation; International 10 -20 system). Bipolar derivation of CS2-Fz was used to record N13 (potential generated in the cuneate nucleus) (Allison and Hume 1981;Araki et al 1997;Desmedt and Cheron 1981;Kaji et al 1986;Morioka et al 1991;Sonoo et al 1999). The derivation CPc-NC was used to evaluate P13/14 (potential generated in the medial lemniscus).…”

Section: Median Nerve Sepsmentioning

confidence: 99%

Very Fast Oscillations Evoked by Median Nerve Stimulation in the Human Thalamus and Subthalamic Nucleus

Hanajima¹,

Chen²,

Ashby³

et al. 2004

Journal of Neurophysiology

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Dostrovsky. Very fast oscillations evoked by median nerve stimulation in the human thalamus and subthalamic nucleus. J Neurophysiol 92: 3171-3182, 2004. First published May 19, 2004 doi:10.1152/ jn.00363.2004. Very fast oscillations (VFOs; 500 -1,500 Hz) are associated with sensory-evoked potentials (SEPs), but their origin is unknown. To characterize the origins of VFOs, we studied 35 patients with deep brain stimulation (DBS) electrodes [15 with thalamic and 20 with the subthalamic nucleus (STN) electrodes]. We recorded median nerve stimulation-evoked SEPs from the thalamus and STN with microelectrodes during stereotactic surgery and from the contacts of the DBS electrodes postoperatively. We also examined the firing of individual neurons in thalamus in relation to the VFOs. In the thalamus, VFOs with frequencies around 1,000 Hz were superimposed on slow potentials. Both slow and fast SEP components showed phase reversals in the somatosensory thalamus [ventralis caudalis (Vc)]. Median nerve poststimulus time histograms showed that single thalamic neurons fired at preferred times at intervals between 0.8 to 1.2 ms that were synchronous with the VFOs, although the neurons fired only once or a few times per trial. In the STN, low-amplitude SEPs with VFOs were observed at a latency similar to the thalamic SEPs. The VFOs from STN probably represent volume conduction, possibly from the medial lemniscus. We conclude that the thalamic VFOs are generated within Vc and that they induce time-locked firing in a network of neurons.

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“…Im Weiteren Verlauf wird über dem Erbschen Punkt das N10-Potenzial des Plexus brachialis im wurzelnahen Bereich erfasst [25]. 26,27]. Die Problematik hinsichtlich der Differenzierung zwischen dem N13a-und N13b-Potenzial, insbesondere bei Ableitung gegen eine Fz-Referenz, reduziert zusätzlich die klinische Bedeutung dieses Potenzials [28].…”

Section: Anatomische Grundlagen Somatosensorisch Evozierter Hirnstammunclassified

Hirnstammdiagnostik mittels somatosensibel evozierter Potenziale nach Nervus-medianus-Stimulation

Koehler¹

2003

Klin Neurophysiol

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Dissociation between upper and lower neck N13 potentials following paired median nerve stimuli

Cited by 24 publications

References 28 publications

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Very Fast Oscillations Evoked by Median Nerve Stimulation in the Human Thalamus and Subthalamic Nucleus

Hirnstammdiagnostik mittels somatosensibel evozierter Potenziale nach Nervus-medianus-Stimulation

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