Dissipation kinetics and dietary risk assessment of spiromesifen on major summer vegetables using good agricultural practices

Dubey, Jatiender Kumar; Katna, Sapna; Shandil, Deepika; Devi, Nisha; Singh, Gaganpreet; Singh, Gagandeep; Singh, Shubhra; Kaushik, Ekta; Sharma, Ajay

doi:10.1002/bmc.5085

Cited by 9 publications

(4 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For spiromesifen, the current results were roughly comparable with half-lives of 0.93–1.38 days for tomato [ 30 ], 1.6, 1.8, 1.9, and 1.7 days for okra, bell pepper, chili, and brinjal, respectively [ 31 ], and 1.32–2.18 days for brinjal [ 32 ]. In contrast, a few reports have investigated the longer half-life of spiromesifen in different crops: 5.5–6.2 days, 2.52–2.88 days, and 5.0–8.5 days in apple, eggplant, and leaf tea, respectively [ 13 , 33 , 34 , 35 ], and 6–6.5 days in tomato [ 14 ].…”

Section: Resultssupporting

confidence: 66%

Terminal Residues and Risk Assessment of Spiromesifen and Spirodiclofen in Tomato Fruits

Abdallah

El-Hamid

Ahmed

et al. 2023

Plants

View full text Add to dashboard Cite

Insecticides are important to increase crop yields, but their overuse has damaged the environment and endangered human health. In this study, residues of spiromesifen and spirodiclofen were determined in tomato fruit using a simple and efficient analytical procedure based on acetonitrile extraction, extract dilution, and UPLC-MS/MS. The linearity range was 1–100 µg/kg and 0.5–100 µg/kg, and the correlation coefficient (R2) and residuals were ≥0.9991 and ≤16.4%, respectively. The limit of determination (LOD) was 0.26 and 0.08 µg/kg, while the limit of quantification (LOQ) was verified at 5 µg/kg. The relative standard deviation of spiked replicates at 5 µg/kg analyzed in one day (RSDr, n = 6) was ≤8.35%, and within three different days (RSDR, n = 18) it was ≤15.85%, with recoveries exceeding 91.34%. The method recovery test showed a satisfactory value of 89.23–97.22% with an RSD of less than 12.88%. The matrix effect was determined after a 4-fold dilution of the raw extract and was −9.8% and −7.2%, respectively. The validated method was used to study the dissipation behavior of the tested analytes in tomato fruit under field conditions. First-order kinetics best described the dissipation rates. The calculated half-lives were 1.49–1.83 and 1.91–2.38 days for spiromesifen and spirodiclofen, respectively, after application of the authorized and doubled authorized doses, indicating that spiromesifen dissipated more rapidly than spirodiclofen. The final residue concentrations of spiromesifen and spirodiclofen were 0.307–0.751 mg/kg and 0.101–0.398 mg/kg, respectively, after two or three applications, and were below the European Union (EU) maximum residue limits. The chronic risk assessment indicates that both insecticides are safe for adult consumers.

show abstract

Section: Resultssupporting

confidence: 66%

Terminal Residues and Risk Assessment of Spiromesifen and Spirodiclofen in Tomato Fruits

Abdallah

El-Hamid

Ahmed

et al. 2023

Plants

View full text Add to dashboard Cite

show abstract

“…The linearity approach assesses sensitivity at various dosages (Sharma et al, 2021). For precision and accuracy, the samples were spiked with all the test pesticides at 0.05, 0.10, 0.25, 0.50, and 1.00 mg/kg fortification levels and replicated five times (Dubey et al, 2021). The percentage RSD (relative standard deviation) and recovery must be less than 20 and 70–120%, respectively (SANTE, 2019).…”

Section: Methodsmentioning

confidence: 99%

Dissipation pattern and dietary risk assessment of some commonly used insecticides on tomato (Solanum lycopersicum L.)

Singh

Dubey

Katna

et al. 2022

Biomedical Chromatography

Self Cite

View full text Add to dashboard Cite

Pesticide residue in food commodities is a serious concern in relation to consumer safety and also the most significant barrier in the trade of food commodities. The dissipation pattern of four insecticides, namely novaluron, λ‐cyhalothrin, imidacloprid, and fenazaquin, was evaluated on tomato fruits and cropped soil. The residues were extracted using the QuEChERS analytical method and quantized using a gas chromatograph with electron capture detector, gas chromatograph mass spectrometer, and high‐performance liquid chromatography with photo diode array detector. The analytical method was validated using parameters like recovery, linearity, accuracy, matrix effect, and specificity, with limit of detection and limit of quantitation established to be 0.01 and 0.05 mg/kg, respectively, for all the pesticides. The average initial deposits (samples collected after 2 h of application) at the recommended dose of novaluron, λ‐cyhalothrin, imidacloprid, and fenazaquin were 0.593, 0.293, 0.227, and 0.431 mg/kg on tomato fruits, respectively, and were below the limit of quantification in soil. The pre‐harvest interval of 17, 8, 1, and 13 days was suggested for novaluron, λ‐cyhalothrin, imidacloprid, and fenazaquin on tomato, respectively. Risk assessment studies revealed that all pesticides under study are safe and do not pose any threat to humans as theoretical maximum dietary intake is less than the maximum permissible intake and acceptable daily intake.

show abstract

“…The current ndings were approximately in line with the spiromesifen of half-lives, which for tomatoes range from 0.93 to 1.38 days these reported by Sharma et al (2014). In some summery vegetables-okra, capsicum, chilli, (aubergine)-the residues of spiromesifen halfdissipated in 1.6, 1.8, 1.9, and 1.7 days, respectively studied by Dubey et al (2021).…”

Section: Analysing Of Spiromesifen On Both Tomato Fruits and Leavesmentioning

confidence: 99%

Residue Evaluation of Spiromesifen in Tomato fruits, Leaves, and Soil in Baghdad-Iraq using QuEChERS Extraction via FID-Gas Chromatography

Kadhum,

Hammood,

Arif

2023

Preprint

View full text Add to dashboard Cite

Spiromesifen is an insecticide used to control whiteflies, red spider mites, and other pests in agriculture. This study has investigated a selective gas chromatography (GC) analytical method to determine spiromesifen residue levels in tomato fruits, leaves, and soil. Samples were extracted and cleaned utilizing a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method prior to GC analysis. Validation studies were performed by spiking blank tomato fruits, leaves, and soil samples at 0.5, 1, and 10 µg/mL spiromesifen. Satisfactory recoveries were achieved with percentage recoveries of 98.74%, 93.92%, and 94.18% for fruits, leaves, and soil, respectively. Negligible matrix effects were observed, with values of -7.9%, -7.8%, and − 5.3% for fruits, leaves, and soil correspondingly. The method exhibited strong linearity across a spiromesifen concentration range of 0.002-20 µg/mL, with R2 values exceeding 0.9900. Repeatability was also demonstrated via relative standard deviations of < 3%. Confirmatory studies were performed via GC–MS in selective ion monitoring mode within a mass range of 271–274 (m/z). Under greenhouse conditions, spiromesifen residues on the tomato fruits, leaves and soil were 3.39, 8.24 and 1.39 mg.kg− 1, respectively. The dissipation of spiromesifen residues followed first-order rate kinetics and degraded within a dissipation time of 50% of 1.6 days. This study was indicates that the proposed GC analytical methodology enables selective, accurate, and precise quantification of spiromesifen residues in tomato fruits, leaves, and soil. The method could be utilized for monitoring spiromesifen levels in agricultural environments to ensure compliance with insecticide regulations.

show abstract

Dissipation kinetics and dietary risk assessment of spiromesifen on major summer vegetables using good agricultural practices

Abstract: Dissipation kinetics and dietary risk assessment of spiromesifen is worked out on four summer vegetables, viz. okra, chilli, capsicum and brinjal (eggplant or aubergine) during March-April 2015 at the experimental farm of the

Cited by 9 publications

References 25 publications

Terminal Residues and Risk Assessment of Spiromesifen and Spirodiclofen in Tomato Fruits

Terminal Residues and Risk Assessment of Spiromesifen and Spirodiclofen in Tomato Fruits

Dissipation pattern and dietary risk assessment of some commonly used insecticides on tomato (Solanum lycopersicum L.)

Residue Evaluation of Spiromesifen in Tomato fruits, Leaves, and Soil in Baghdad-Iraq using QuEChERS Extraction via FID-Gas Chromatography

Contact Info

Product

Resources

About