Dissemination of Resistance and Virulence Determinants in Methicillin-Resistant Staphylococcus aureus During Colonization and Disease: A Review

Bitrus, Asinamai Athliamai; Zunita, Z.; Goni, Mohammed Dauda; Mshelia, Innocent Thlama

doi:10.17582/journal.aavs/2018/6.1.44.54

Cited by 2 publications

(1 citation statement)

References 61 publications

(96 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…B i t r u s et al [3] explained that multi-drug resistance in S. aureus may be partly attributed to the acquisition of resistance determinants domiciled in mobile genetic elements. L a y et al [18] also opined that the determinants of multi-drug resistance are capable of being disseminated in a region or between regions because of antibiotic selective pressure in either livestock or humans.…”

Section: Discussionmentioning

confidence: 99%

Occurrence and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus Aureus (Mrsa) in Layer Chickens in Kebbi, Nigeria

Gaddafi¹,

Yakubu²,

Bellò

et al. 2022

Folia Veterinaria

View full text Add to dashboard Cite

Antimicrobial resistance (AMR) is a global health threat, and antimicrobial use in animal production for growth enhancement or prophylaxis contributes to the development of AMR. A cross-sectional study was conducted to investigate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in poultry and farm attendants in Kebbi, North-Western Nigeria. A total of 207 cloacal and nasal swabs were randomly collected from four farms comprising 50 samples from each poultry farm and only 7 samples from farm attendants. The samples were analysed using routine bacteriological culture and identification techniques. Presumptive MRSA isolates were confirmed by PCR assay and AMR profiles of the isolates were evaluated using the Kirby-Bauer disk diffusion method. Of the 207 samples examined, 37.5 % (75/200) of layer birds tested positive for MRSA and 71.4 % (5/7) of farm attendants were MRSA positive. All the isolates were susceptible to vancomycin, with an AMR index ˃ 0.3. The findings of this study indicated colonization of layer chickens and humans by multidrug resistant MRSA, thus highlighting the potential role of poultry sources of transmission of multidrug-resistant MRSA strains to humans and vice versa.

show abstract

Section: Discussionmentioning

confidence: 99%