Disseminated tuberculosis infection: a ‘super’ 18F-FDG PET/CT appearance

Nordin, Abdul Jalil; Rossetti, Claudio; Rahim, Normaliza Abd

doi:10.1007/s00259-009-1107-z

Cited by 6 publications

(5 citation statements)

References 4 publications

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“…Some reports and clinical studies have dealt with the usefulness of 18 F-FDG-PET-CT for the diagnosis and monitoring of pulmonary tuberculosis [9,10]. PET scans using 18 F-FDG are useful for differentiating tuberculous pulmonary nodules from malignancies but can also provide information about disease activity, enabling the immediate start of antitubercular treatment before a definite diagnosis based on bacteriology, which is time-consuming and sometimes produces false-negative results, becomes available in patients with active pulmonary tuberculosis [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Constrictive tuberculous pericarditis diagnosed using 18F-fluorodeoxyglucose positron emission tomography: a report of two cases

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Constrictive tuberculous pericarditis diagnosed using 18F-fluorodeoxyglucose positron emission tomography: a report of two cases

et al. 2010

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“…18 F-FDG-PET/CT may frequently reveal disseminated TB, which may mimic malignancy. [114][115][116] Several cases have been reported in literature. Nuclear physicians must have a high index of suspicion of TB when interpreting 18 F-FDG-PET/CT in TB endemic areas or migrants from such countries.…”

Section: Tb Mimicking Disseminated Malignancymentioning

confidence: 99%

“…Super 18 F-FDG scan has been described in a case with high TB disease burden with diminished 18 F-FDG uptake at physiologic sites. 116…”

Section: Tb Mimicking Disseminated Malignancymentioning

confidence: 99%

Tuberculosis

Ankrah

Glaudemans

Maes

et al. 2018

Seminars in Nuclear Medicine

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Tuberculosis (TB) is currently the world's leading cause of infectious mortality. Imaging plays an important role in the management of this disease. The complex immune response of the human body to Mycobacterium tuberculosis results in a wide array of clinical manifestations, making clinical and radiological diagnosis challenging. F-FDG-PET/CT is very sensitive in the early detection of TB in most parts of the body; however, the lack of specificity is a major limitation.F-FDG-PET/CT images the whole body and provides a pre-therapeutic metabolic map of the infection, enabling clinicians to accurately assess the burden of disease. It enables the most appropriate site of biopsy to be selected, stages the infection, and detects disease in previously unknown sites. F-FDG-PET/CT has recently been shown to be able to identify a subset of patients with latent TB infection who have subclinical disease. Lung inflammation as detected byF-FDG-PET/CT has shown promising signs that it may be a useful predictor of progression from latent to active infection. A number of studies have identified imaging features that might improve the specificity of F-FDG-PET/CT at some sites of extrapulmonary TB. Other PET tracers have also been investigated for their use in TB, with some promising results. The potential role and future perspectives of PET/CT in imaging TB is considered. Literature abounds on the very important role ofF-FDG-PET/CT in assessing therapy response in TB. The use of F-FDG for monitoring response to treatment is addressed in a separate review.

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“…1 The use of FDG whole-body PET scanning has also been described for monitoring disseminated TB. 2,3 Immune deficiency in Non-Hodgkin's lymphoma (NHL) may result in infections 4,5 and coexistence of NHL and TB has been reported earlier. [6][7][8] Since symptoms and signs may be shared, initial therapeutic failure during the treatment of either NHL or TB should raise the possibility of simultaneous occurrence of both diseases.…”

Section: Introductionmentioning

confidence: 99%

Coexisting Tuberculosis and Non-Hodgkin's Lymphoma on 18F-Fluorodeoxyglucose PET-CT

Kashyap¹,

Mittal²,

Bhattacharya³

et al. 2012

Journal of Postgraduate Medicine, Education and Research

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Non-Hodgkin's lymphoma (NHL) has been related to immune deficiency and may be preceded by chronic inflammatory diseases. Tuberculosis (TB), on the other hand, is a chronic infectious disease whose presentation and reactivation is known to be promoted by cell mediated immunodeficiency. The coexistence of NHL and TB in the same patient is not uncommon, and PET/CT using F-18 fluorodeoxyglucose (FDG) may show tracer-avid lymph nodes in both conditions. This case illustrates the importance of FDG PET/CT guided biopsy in confirming a diagnosis of concurrent NHL and TB. How to cite this article Bhattacharya A, Agrawal KL, Kashyap R, Manohar K, Mittal BR, Varma SC, Dey P, Das A. Coexisting Tuberculosis and Non-Hodgkin's Lymphoma on 18F-Fluorodeoxyglucose PET-CT. J Postgrad Med Edu Res 2012;46(1):49-50.

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Disseminated tuberculosis infection: a ‘super’ 18F-FDG PET/CT appearance

Cited by 6 publications

References 4 publications

Constrictive tuberculous pericarditis diagnosed using 18F-fluorodeoxyglucose positron emission tomography: a report of two cases

Constrictive tuberculous pericarditis diagnosed using 18F-fluorodeoxyglucose positron emission tomography: a report of two cases

Tuberculosis

Coexisting Tuberculosis and Non-Hodgkin's Lymphoma on 18F-Fluorodeoxyglucose PET-CT

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