2004
DOI: 10.1038/sj.bmt.1704740
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Disseminated tuberculosis following reduced-intensity cord blood transplantation for adult patients with hematological diseases

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Cited by 39 publications
(47 citation statements)
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“…There is an increase in such cases because umbilical cord blood has been increasingly utilized as a source of hematopoietic stem cells for transplantation of patients with advanced and high-risk hematological diseases without favorable donors. Cord blood transplantation (CBT) often presents a prolonged immunological deficiency and is complicated with various early severe infections such as bacteremia, cytomegalovirus (CMV) disease, tuberculosis, and fungal infection [4,5].…”
Section: Introductionmentioning
confidence: 99%
“…There is an increase in such cases because umbilical cord blood has been increasingly utilized as a source of hematopoietic stem cells for transplantation of patients with advanced and high-risk hematological diseases without favorable donors. Cord blood transplantation (CBT) often presents a prolonged immunological deficiency and is complicated with various early severe infections such as bacteremia, cytomegalovirus (CMV) disease, tuberculosis, and fungal infection [4,5].…”
Section: Introductionmentioning
confidence: 99%
“…This delay places patients at higher risk of mortality, which has been reported to be 25-30%. 5 On review of the literature of disseminated cases of tuberculosis in stem cell transplant patients, diagnosis was usually made from bronchial lavage or bone marrow biopsy [6][7][8][9][10][11] (Table 1). There was one case who had skin biopsy confirming cutaneous involvement in addition to previously established disease.…”
mentioning
confidence: 99%
“…1,2 Although Mycobacterium tuberculosis (TB) infection is uncommon in UCBT recipients, few available reports [3][4][5] suggest a more severe clinical course as compared with the TB infections in auto-and allo-SCT recipients. [6][7][8] Here, we report a case of TB following UCBT and discuss its clinical characteristics and challenges.…”
mentioning
confidence: 99%