Disseminated rhinosporidiosis with conjunctival involvement in an immunocompromised patient

Case Report of Nasal Rhinosporidiosis in South Africa

“…Highest incidence is reported in male persons <40 years of age, presumably because of increased exposure as a result of the nature and extent of their outdoor activities ( 4 , 5 ). The eukaryotic pathogen typically infects exposed nasal, ocular, or genitourinary tract mucosal membranes, with rare reports of cutaneous or disseminated spread in both immunocompetent and immunocompromised patients ( 1 , 4 , 6 , 7 ). The etiologic agent is R. seeberi (class: Mesomycetozoea).…”

“…Treatment of rhinosporidiosis is limited to the surgical removal of polyps and electrocauterization at the attachment base; some clinicians prescribe a prolonged postoperative course of diaminodiphenyl sulfone (dapsone) alone or as part of a multidrug antimicrobial regimen ( 4 – 7 ). Although not curative, those adjuvants are thought to impede sporangial and endospore maturation.…”