Disseminated Mycobacterial Infection With Reactive Polyarthritis (Poncet’s Disease) During Immune-suppressive Treatment Including Ustekinumab for Pediatric Crohn’s Disease
Chiara Minotti,
Paola Costenaro,
Daniele Donà
et al.
Abstract:Background:
The incidence of pediatric inflammatory bowel disease is increasing. tumor necrosis factor alpha inhibitors medicines improved the prognosis of affected subjects. Nonetheless, a proportion of patients do not respond or lose response to treatment. Newer biologics, like ustekinumab, have been approved for adults. The pediatric off-label use of these drugs is increasing, despite limited safety evidence. We report a case of disseminated mycobacterial infection (MI) presenting with reactive … Show more
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