Disseminated histoplasmosis of adrenal gland

Dwivedi, M. P.; Piparsania, B; Issar, P; Dewangan, L

doi:10.4103/0971-3026.32291

Cited by 8 publications

(4 citation statements)

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“…The clinical manifestation of chronic disseminated histoplasmosis resemble those of other chronic infection such as TB. Usually these patients presents with low grade fever, weight loss, anorexia, night sweats, and with the features of adrenal insufficiency . In 99% cases infection is subclinical.…”

Section: Discussionmentioning

confidence: 99%

Fine‐needle aspiration cytology of non‐neoplastic adrenal pathology

Kumar

Dey

2016

Diagnostic Cytopathology

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Section: Discussionmentioning

confidence: 99%

Fine‐needle aspiration cytology of non‐neoplastic adrenal pathology

Kumar

Dey

2016

Diagnostic Cytopathology

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“…In 99% cases infection is subclinical. Incidence is 2–5% in HIV patients and < 0.05% in non‐HIV patient 7…”

Section: Discussionmentioning

confidence: 99%

Bilateral adrenal histoplasmosis in immunocompetent patients

Rana

Krishnani

Kumari

2011

Diagnostic Cytopathology

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Histoplasmosis is a fungal infection caused by Histoplasma capsulatum, which commonly presents as transient pulmonary infection that usually subsides without treatment. Disseminated histoplasmosis may affect almost all systems, including the reticuloendothelial system, lungs, gastrointestinal tract, renal tract, central nervous system, bone marrow, and adrenal glands. Adrenal gland is frequently involved in disseminated histoplasmosis but commonly present as unilateral mass; bilateral involvement is rare. It is also rare in immunocompetent hosts and only few cases have been reported in past. We report four cases of adrenal histoplasmosis with bilateral involvement. These cases were initially diagnosed cytopathologically on fine needle aspirations performed on adrenal glands. All these patients were immunocompetent and two of them also had associated adrenal insufficiency. Diagnosis of adrenal histoplasmosis can be easily made on fine needle aspiration cytology. Adrenal histoplasmosis can occur in immunocompetent individuals and should be considered in differential diagnosis of bilateral adrenal masses in immunocompetent individuals.

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“…[ 4 ] Incidence is reported to be 2–5% in acquired immunodeficiency patients (AIDS) patients and <0.05% in non-HIV patients. [ 5 ]…”

Section: Discussionmentioning

confidence: 99%

Primary cutaneous histoplasmosis in a HIV-positive individual

Vasudevan

Amitabh

2010

J Global Infect Dis

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A 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary lymphadenopathy. There was history of local injury on the face 6 months prior to the development of symptoms. Skin biopsy revealed multiple round to oval spores with surrounding halo intracellularly, confirming the diagnosis of cutaneous histoplasmosis. No systemic involvement was detected on further investigations. The patient responded to oral antifungals in a short duration, confirming the local nature of the presentation. This is probably the first time in the literature that a primary cutaneous manifestation of histoplasmosis is being described in an immunocompromised individual.

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Disseminated histoplasmosis of adrenal gland

Cited by 8 publications

References 0 publications

Fine‐needle aspiration cytology of non‐neoplastic adrenal pathology

Fine‐needle aspiration cytology of non‐neoplastic adrenal pathology

Bilateral adrenal histoplasmosis in immunocompetent patients

Primary cutaneous histoplasmosis in a HIV-positive individual

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