Disseminated histoplasmosis in an HIV/AIDS transgender male‐to‐female with atypical and persistent GI manifestations

Abstract

Disseminated histoplasmosis is a rare complication of infection due to Histoplasma capsulatum. Typically, histoplasmosis is self‐limiting and asymptomatic in infected individuals with immunocompetence. Disseminated disease, however, can arise in high‐risk populations with primary or acquired cellular immunodeficiency including HIV/AIDS, transplant recipients, and those undergoing immunosuppressive therapy. Here we describe a unique case of extrapulmonary gastrointestinal histoplasmosis by infiltrative Peyer's patch disease with bone marrow involvement in a transgender HIV‐infected woman.