Disseminated Cryptococcosis Presenting as Molluscum‐like Lesions as the First Manifestation of Aids

The Diagnosis, Staging, and Treatment Options for Mycosis Fungoides

“…A number of infectious agents have been investigated, including human T-cell lymphotropic virus (HTLV) I/II, human immunodeficiency virus (HIV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human simplex virus (HSV). 17,[19][20][21][22][23] At the forefront of etiologic research has been the hypothesis of a retroviral cause of MF. HTLV-I has a causal relation to adult T-cell leukemia/lymphoma.…”

“…Thus, the role of retroviruses in MF remains uncertain. [14][15][16][17][18][19][20][21][22][23][24][25][26] Perhaps HTLV-I plays a role in only a subset of MF cases.…”

Molluscum‐like cutaneous cryptococcosis: a histopathological and pathogenetic appraisal

“…Currently, the clinical purview of CC includes papules, nodules, ulcers, pustules, purpura, vesiculobullous lesions, draining sinuses and granulomas 6–15 . Furthermore, CC not only mimics other dermatoses 6–15 and neoplasms 16 but also other infections, such as cellulites, 14 herpes simplex, 15 syphilis, 17 tuberculosis 17 and molluscum contagiosum 13,15,17–24 . Because of the clinical similarity with other cutaneous diseases, 6–15 microscopic assessment is crucial for the diagnostic confirmation of CC.…”

“…Molluscum‐like cutaneous cryptococcosis (MLCC), first described in 1985, 18 is characterized by hypopigmented or skin‐colored papules with central umbilication and variable crust formation. The clinical features of molluscum contagiosum, CC and MLCC are well documented, as are the histomorphologic characteristics of molluscum contagiosum and cryptococcosis 6–15,17–27 . However, the histomorphological nuances of C. neoformans infection that effect mimicry of molluscum contagiosum are undocumented.…”