Disseminated Cryptococcosis Presenting as Cutaneous Cellulitis in an Adolescent with Systemic Lupus Erythematosus

Valente, Ellen Simionato; Lazzarin, Mauricio Costa; Koech, Bruno Lopes; Rosa, Ralph Vighi da; Almeida, Rafael de; Oliveira, Umberto Lopes de; Neugebauer, Maria Gertrudes Fernandes Pereira; Sacco, Alexander Gonçalves

doi:10.4081/idr.2015.5743

Cited by 15 publications

(19 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 4 , 8 In immunosuppressed patients, such as solid organ transplant patients, the cutaneous presentation can simulate other conditions such as bacterial cellulitis or panniculitis, clinically indistinguishable, in many cases leading to delay in diagnosis and appropriate treatment. 1 , 6 - 9 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Disseminated cryptococcosis with skin lesions: report of a case series

Hayashida

Seque

Pasin

et al. 2017

An. Bras. Dermatol.

View full text Add to dashboard Cite

Cryptococcosis is a common fungal infection in immunocompromised patients, caused by genus Cryptococcus, presenting with meningitis, pneumonia, and skin lesions. Cutaneous presentation can be varied, but specifically in solid organ transplant recipients (iatrogenically immunocompromised), cryptococcosis should always be considered in the differential diagnosis of cellulitis-like lesions, since the delay in diagnosis leads to worse prognosis and fatal outcome. We report four cases of cryptococcosis with cutaneous manifestation not only for its rarity, but also to emphasize the important role of the dermatologist in the diagnosis of this disease.

show abstract

Section: Discussionmentioning

confidence: 99%

“… 3 In the immunocompromised patients, cryptococcosis must always be considered in the differential diagnosis of cellulitis-like or molluscum contagiosum-like lesions, because the delay in diagnosis can lead to a worse prognosis. 6 …”

Section: Introductionmentioning

confidence: 99%

Disseminated cryptococcosis with skin lesions: report of a case series

Hayashida

Seque

Pasin

et al. 2017

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

“…Primary cutaneous cryptococcosis can occur in both immunocompetent [ 11 ] and immunocompromised people [ 12 , 13 ]. Only 10–15% of disseminated cryptococcal infection cases have cutaneous manifestations, and males seem to be more susceptible to cutaneous cryptococcosis [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic Meningitis and Lung Cavity in a Case of Cryptococcosis

Guo

et al. 2017

Am J Case Rep

View full text Add to dashboard Cite

Patient: Male, 52Final Diagnosis: CryptococcosisSymptoms: Forehead skin lesions and feverMedication: —Clinical Procedure: —Specialty: Infectious DiseasesObjective:Unusual clinical courseBackground:Cryptococcus neoformans (C. neoformans) infection is one of the most common opportunistic infections in AIDS patients. C. neoformans usually infects the central nervous system (CNS) and/or lungs with typical clinical manifestation.Case Report:Here, we report the case of a 52-year-old HIV-1-infected man with disseminated cryptococcosis, including sub-acute meningitis, pulmonary, and cutaneous cryptococcosis, but only skin lesion served as the chief complaint. Moreover, the results of cerebrospinal fluid (CSF) tests and lung computed tomography (CT) scan were atypical.Conclusions:We present the clinical characteristics of this case and discuss the diagnostic procedure, which will likely help clinicians in making a timely definitive diagnosis of this disease.

show abstract

“…Some reports indicate that Cryptococcosis of the central nervous system and Analysis of the ITS1 and ITS2 regions pulmonary infection; are common in patients who express the disseminated disease [34]. The fungus can lead the patient to extensive fibrosis in the subarachnoid space to find small veins, inducing venous congestion, causing cerebral infarction, and thus may be fatal [35].…”

Section: Clinical Presentation Of Cryptococcosismentioning

confidence: 99%