Dissection of Porcine Ascending Aortic Media: Mechanical Characterization and Multiscale Model

Abstract

Ascending thoracic aortic aneurysm (aTAA) is a pathological condition with a high risk of dissection and rupture. Clinically, management of aTAA balances the risk of rupture with that of surgery-related complications. The risk of aneurysm rupture is known to correlate with aneurysm diameter. 1,2 Aneurysms greater than 6 cm in diameter have a significantly higher risk of rupture. 1 Current guidelines for intervention suggest surgical intervention for aTAA diameters greater than 5.5cm for patients without connective tissue disorders. 1