Dissecting Retropharyngeal Abscess Due to Fusobacterium necrophorum in an Adult

Mukau, Leslie

doi:10.1097/00007611-198504000-00029

Cited by 12 publications

(4 citation statements)

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“…Patients with this presentation will develop empyema in the absence of underlying lung lesions. In the current review, 4/222 fitting the case definition for Lemierre's syndrome had mediastinitis (191,266,274,280), 3 of which involved F. necrophorum (191,266,280). Three other cases of F. necrophorumassociated mediastinitis were identified.…”

Section: Mediastinitismentioning

confidence: 77%

Human Infection withFusobacterium necrophorum(Necrobacillosis), with a Focus on Lemierre's Syndrome

2007

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SUMMARYSummary:Human infection withFusobacterium necrophorumusually involvesF. necrophorumsubsp.funduliformerather thanF. necrophorumsubsp.necrophorum, which is a common pathogen in animals. Lemierre's syndrome, or postanginal sepsis, is the most common life-threatening manifestation. Tonsillitis is followed by septic thrombophlebitis of the internal jugular vein and then a septicemia with septic emboli in lungs and other sites. Recent evidence suggests thatF. necrophorumcan be limited to the throat and cause persistent or recurrent tonsillitis.F. necrophorumis unique among non-spore-forming anaerobes, first for its virulence and association with Lemierre's syndrome as a monomicrobial infection and second because it seems probable that it is an exogenously acquired infection. The source of infection is unclear; suggestions include acquisition from animals or human-to-human transmission. Approximately 10% of published cases are associated with infectious mononucleosis, which may facilitate invasion. Recent work suggests that underlying thrombophilia may predispose to internal jugular vein thrombophlebitis. Lemierre's syndrome was relatively common in the preantibiotic era but seemed to virtually disappear with widespread use of antibiotics for upper respiratory tract infection. In the last 15 years there has been a rise in incidence, possibly related to restriction in antibiotic use for sore throat.

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Section: Mediastinitismentioning

confidence: 77%

Human Infection withFusobacterium necrophorum(Necrobacillosis), with a Focus on Lemierre's Syndrome

2007

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“…Other wise, one might speculate that earlier intervention with CRRT may have a favorable impact on outcome. Com monly observed cardiac and/or pulmonary system failure accompanying postoperative ARF may be exacerbated (or provoked) by overhydration [35] and increases the risk of death [36]. Therefore, prevention or the rapid reversal of any existing overhydration with the early institution of CRRT may lead to a diminution of additional vital organ dysfunctions.…”

Section: Discussionmentioning

confidence: 99%

Acute Dialytic Support for the Critically III: Intermittent Hemodialysis versus Continuous Arteriovenous Hemodiafiltration

Bommel¹,

Bouvy

et al. 1995

Am J Nephrol

123

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There is still debate about whether continuous renal replacement therapy is superior to intermittent hemodialysis (IHD) as dialytic support for the critically ill patient with acute renal failure, mainly because of lack of comparative data. We sought to address this issue by reviewing the medical records of such patients admitted to a single surgical intensive care unit treated with either continuous arteriovenous hemodiafiltration (CAVHD) or IHD between January 1, 1986, and August 31, 1993. Of 94 consecutive patients who received dialytic support for severe acute renal failure, 34 (36%) patients were treated with IHD and 60 (64%) patients with CAVHD. The patients were comparable in terms of age or gender and represented a similar case mix. Patients treated with CAVHD were more severely ill as manifested by a lower mean arterial pressure (75 ± 3 vs. 86 ± 5 mm Hg; p < 0.05), higher Apache II score (26.5 ± 0.5 vs. 22.2 ± 0.3; p < 0.05), and a higher number of organ system failures (3.4 ± 0.2 vs. 2.6 ± 0.3; p < 0.05). Despite greater illness severity and a higher probability of death (55 ± 2.6 vs. 33 ± 2.5%; p < 0.0001), in those treated with CAVHD, no difference in outcome was observed between groups: CAVHD 26/60 (43%) vs. IHD 20/34 (59%; NS). The mean Apache II score of patients treated with CAVHD who survived was similar to that of patients treated with IHD who died (24.5 ± 0.3 vs. 24.2 ± 0.4; NS). CAVHD was associated with improved hemodynamic stability, better control of fluid balance and biochemistry, increased nutritional intake, and a shorter duration of acute renal failure (p < 0.05). Our data suggest that CAVHD offers several distinct advantages over IHD which may translate in improved survival, particularly in the more severely ill patients.

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“…Mukau [13] treated a patient with dissecting retropharyngeal abscess due to Fusobacterium necrophorum that was complicated by pneumonia, mediastinitis, pericarditis, sepsis and status epilepticus.…”

Section: Microbiologymentioning

confidence: 99%

Pericarditis caused by anaerobic bacteria

Brook

2009

International Journal of Antimicrobial Agents

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Dissecting Retropharyngeal Abscess Due to Fusobacterium necrophorum in an Adult

Cited by 12 publications

References 0 publications

Human Infection withFusobacterium necrophorum(Necrobacillosis), with a Focus on Lemierre's Syndrome

Human Infection withFusobacterium necrophorum(Necrobacillosis), with a Focus on Lemierre's Syndrome

Acute Dialytic Support for the Critically III: Intermittent Hemodialysis versus Continuous Arteriovenous Hemodiafiltration

Pericarditis caused by anaerobic bacteria

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