Disrupted functional connectivity of the habenula links psychomotor retardation and deficit of verbal fluency and working memory in late‐life depression
Ting Su,
Ben Chen,
Mingfeng Yang
et al.
Abstract:BackgroundFunctional abnormalities of the habenula in patients with depression have been demonstrated in an increasing number of studies, and the habenula is involved in cognitive processing. However, whether patients with late‐life depression (LLD) exhibit disrupted habenular functional connectivity (FC) and whether habenular FC mediates the relationship between depressive symptoms and cognitive impairment remain unclear.MethodsOverall, 127 patients with LLD and 75 healthy controls were recruited. The static … Show more
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