Disproportionate increase in prevalence of diabetes among patients with congestive heart failure due to systolic dysfunction

Higher BMI in heart failure patients is associated with longer survival only in the absence of diabetes

“…that reported in other heart failure studies, usually between 20 and 30%. [26][27][28] The finding of the current analysis suggesting that a higher BMI confers survival benefit for heart failure patients and that low-normal weight is associated with higher risk of death is concordant with reports in the past few years also documenting a relationship between higher BMI and better prognosis in chronic heart failure. [4][5][6][7][8][9][10]12 Despite this evidence, some authors have questioned whether the relationship between higher BMI and better survival is truly causal.…”

Diastolic Stiffness of the Failing Diabetic Heart

“…The prevalence of DM in heart failure is increasing, 24,25 and mortality and hospitalization rates in diabetic patients with heart failure remain particularly high. 26 -28 Although coronary artery disease is the most important contributor to the myocardial dysfunction observed in DM, DM-related disturbances such as hyperglycemia, insulin resistance, and hyperlipidemia can also act directly on the myocardium 29 and induce myocardial dysfunction because of a shift in myocardial energy production from glucose utilization to fatty acid oxidation.…”

Do Cardioselective β-Adrenoceptor Antagonists Reduce Mortality in Diabetic Patients with Congestive Heart Failure?

“…The incidence of diabetes mellitus among patients with congestive heart failure (CHF) is increasing, [1] with a recent report stating that up to 44% of patients with CHF may have diabetes. [2] b-Adrenoceptor antagonist (b-blocker) therapy is recommended for all patients with CHF due to systolic dysfunction; [3] however, the relative benefits of non-selective b-adrenoceptor antagonist therapy over cardioselective b 1 -adrenoceptor antagonist (CSB) therapy is debatable.…”