Dispositivos de coagulometría portátil en el seguimiento y control ambulatorio de la terapia anticoagulante oral: revisión sistemática

Caballero-Villarraso, Javier; Villegas, R.; Rodríguez-Cantalejo, Fernando

doi:10.1016/j.aprim.2010.03.017

Cited by 5 publications

(1 citation statement)

References 32 publications

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“…In another systematic review, the clinical utility of wearable sensors in patients with Parkinson disease to support clinical decision making was not clear [25]. A 2011 systematic review confirmed no differences between the effectiveness of portable coagulometers and conventional coagulometers in monitoring oral anticoagulation [26].…”

Section: Introductionmentioning

confidence: 99%

Outcomes of Digital Biomarker–Based Interventions: Protocol for a Systematic Review of Systematic Reviews (Preprint)

Motahari-Nezhad¹,

Péntek²,

Gulàcsi³

et al. 2021

Preprint

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BACKGROUND Digital biomarkers are defined as objective, quantifiable physiological and behavioral data that are collected and measured by means of digital devices such as portables, wearables, implantables or digestibles. For their widespread adoption in publicly financed healthcare systems, it is important to understand how their benefits translate into improved patient outcomes, which is essential for demonstrating their value. OBJECTIVE To assess the quality and strength of evidence of the impact of digital biomarkers on clinical outcomes compared to interventions without digital biomarkers, reported in systematic reviews. METHODS A comprehensive search for 2019-2020 will be conducted in the PubMed and the Cochrane Library using keywords related to digital biomarkers and a filter for systematic reviews. Original full-text English publications of systematic reviews comparing clinical outcomes of interventions with and without digital biomarkers via meta-analysis will be included. The AMSTAR-2 tool will be used to assess the methodological quality of reviews. To assess the quality of evidence, we will evaluate systematic reviews using the GRADE tool. To detect the possible presence of reporting bias, we will record whether the protocol of the systematic reviews was published before the start of the study. A qualitative summary of results by digital biomarker technology and outcome will be provided. RESULTS This protocol was submitted before data collection. The next steps in this review will be initiated after the protocol is accepted for publication. CONCLUSIONS Our study will provide a comprehensive summary of the highest level of evidence available on digital biomarker interventions. Our results will help identify clinical areas where the use of digital biomarkers leads to favorable clinical outcomes. In addition, our findings will highlight areas of evidence gaps where the clinical benefits of digital biomarkers have not yet been demonstrated.

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Section: Introductionmentioning

confidence: 99%