Disposable electrochemical sensor prepared using 3D printing for cell and tissue diagnostics

Friman, Hen; Schreiber, D. S.; Inberg, Alexandra; Berkh, O.; Kósa, Gábor; Freeman, Amihay; Shacham‐Diamand, Yosi

doi:10.1016/j.snb.2015.04.065

Cited by 46 publications

(25 citation statements)

References 29 publications

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“…[33] with permission from American Chemical Society; The inset in biochemical analysis was taken from ref. [22] with permission from Elsevier.…”

Section: Discussionmentioning

confidence: 99%

“…An appealing approach for non-invasive diagnostics was to perform the relevant measurements at the immediate apical surface of the targeted cells or issues. Such wonderful idea has been realize by Ragones et al in Tel Aviv University [22]. Compared with traditional three electrodes system, in which the sensing device and the connections to the measurement device were located on the same side of the substrate, they designed a unique 3D sensing platform featuring that the electrical contacts and the sensing electrodes were located vertically on the opposite sides of the same chip.…”

Section: Ec Methodsmentioning

confidence: 99%

“…Furthermore, it was capable of integrating all the analytical stages commonly conducted in a laboratory, including sample pre-treatment, reagent transmission, mixing, reaction, separation, and determination [57,60,69,92]. There is an emerging tendency of constructing new analytical methods for use with 3D printing chip devices, such as, colorimetric method [78,[93][94][95][96], electrochemical (EC) method [22,73,97], chemiluminesce (CL) method [61,98], electrochemiluminescence (ECL) method [31,77], mass spectrometry (MS) analysis [59,67], and fluorescence method [70,92].…”

Section: Chemical Analysis On 3d Printed Lab-on-a-chip Devicesmentioning

confidence: 99%

“…Current micro-fabrication by biocompatible materials is mainly confined to two dimensional (2D) or 2.5D structures without the feasibility of unibody 3D devices [19]. The up-and-coming 3D printing technology, commonly defined as additive manufacturing, is arguably the most promising option to address the limitation [20][21][22]. In recent years, due to its principally advantageous properties, 3D printing has been increasingly used for microfluidic devices construction than conventional methods industrially and academically [23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

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Chemical and biochemical analysis on lab-on-a-chip devices fabricated using three-dimensional printing

Zhang

2016

TrAC Trends in Analytical Chemistry

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“…[33] with permission from American Chemical Society; The inset in biochemical analysis was taken from ref. [22] with permission from Elsevier.…”

Section: Discussionmentioning

confidence: 99%

Section: Ec Methodsmentioning

confidence: 99%

Section: Chemical Analysis On 3d Printed Lab-on-a-chip Devicesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Chemical and biochemical analysis on lab-on-a-chip devices fabricated using three-dimensional printing

Zhang

2016

TrAC Trends in Analytical Chemistry

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“…11,12 Thus, 3D printing provides an alternative method of mass-fabricating electrochemical devices, such as stainless steel electrodes, 13 or electrochemical chips for direct biological measurements. 14 However, the fabrication of electrochemical probes with micron diameters has not been reported with 3D printed devices.…”

Section: Introductionmentioning

confidence: 99%

Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin

Trikantzopoulos

Yang

Ganesana

et al. 2016

Analyst

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Glass insulated carbon-fiber microelectrodes (CFMEs) are standard tools for the measurement of neurotransmitters. However, electrodes are fabricated individually and the glass can shatter, limiting application in higher order mammals. Here, we developed a novel microelectrode batch fabrication method using a 3D-printed mold and polyimide resin insulating agent. The 3D-printed mold is low cost, customizable to change the electrode shape, and allows 40 electrodes to be made simultaneously. The polyimide resin is biocompatible, quick to cure, and does not adhere to the plastic mold. The electrodes were tested for the response to dopamine with fast-scan cyclic voltammetry both in vitro and in vivo and performed similarly to traditional glass-insulated electrodes, but with lower background currents. Thus, polyimide-insulated electrodes can be mass-produced using a 3D-printed mold and are an attractive alternative for making cheap, biocompatible microelectrodes.

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Emerging Applications of Additive Manufacturing in Biosensors and Bioanalytical Devices

Ruan

Wang

Cheng

et al. 2020

Adv Materials Technologies

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The progress of additive manufacturing (AM), known as 3D‐printing, has initiated a revolution in the new generation of biosensors and bioanalytical devices in recent years. The advancement in the resolution of AM has enabled the microfabrication of the architectures of electrodes and sensing layers for high‐performance sensing. Diversiform printable materials, including biocompatible materials, polymers, various gels and metals, have enormously broadened the horizon in sensors and analytical devices for both research and commercial purposes. The considerable shortening of time and cost in sensor prototyping and fabrication has been reported and various highly customizable biosensing platforms and devices are under development. Herein, the most recent studies on the applications of AM in biosensors and bioanalytical devices are summarized with the aim to provide a panorama of emerging 3D‐printing strategies for sensor design and bioanalytical device fabrication.

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Disposable electrochemical sensor prepared using 3D printing for cell and tissue diagnostics

Cited by 46 publications

References 29 publications

Chemical and biochemical analysis on lab-on-a-chip devices fabricated using three-dimensional printing

Chemical and biochemical analysis on lab-on-a-chip devices fabricated using three-dimensional printing

Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin

Emerging Applications of Additive Manufacturing in Biosensors and Bioanalytical Devices

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