Dispersive liquid–liquid microextraction (DLLME) optimization for determination of designer drugs (cathinones) and drugs abuse in oral fluid

Ferreira, Ronise; Fuentes, A.M. Ares; Vázquez, M. Regenjo; Díaz, Antonia María Carro; Sobrino, Alina; Gómez, Purificación Fernández

doi:10.1016/j.toxlet.2016.06.1678

Cited by 1 publication

(1 citation statement)

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“…Therefore, monitoring organic pollutants in the environment is of great significance. However, determination of organic pollutants at trace levels often requires a sample preparation process, such as traditional LLE , SPE , SPME , dispersive liquid–liquid microextraction , pressurized liquid extraction , and stir bar sorptive extraction . Among these methods, SPE has received substantial attention because it is less time consuming, consumes less organic solvent and has higher enrichment factors compared with others .…”

Section: Introductionmentioning

confidence: 99%

Rapid preparation of methyltrimethoxy‐modified magnetic mesoporous silica as an effective solid‐phase extraction adsorbent

Qin

Fan

et al. 2018

J of Separation Science

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A time-saving method was applied to synthesize methyltrimethoxy-modified magnetic mesoporous silica with or without p-toluenesulfonic acid as the catalyst for magnetic solid-phase extraction. The synthesized materials were systematically characterized. Results demonstrated that methyltrimethoxy modified magnetic mesoporous silica with p-toluenesulfonic acid as the catalyst has a relatively smaller aperture and extreme hydrophobicity (water contact angle of 135°). To evaluate the feasibility of these prepared materials as effective adsorbents, it was combined with gas chromatography and electron capture detection to determine 26 polychlorinated biphenyls in environmental water. The result revealed that methyltrimethoxy modified magnetic mesoporous silica with p-toluenesulfonic acid as the catalyst had the best extraction efficiency and recovery. Under the optimized extracted conditions, the proposed method showed good linearity within the concentration range of 5 to 200 ng/L with correlation coefficients of 0.9969 to 0.9999. The limits of detection and quantification based on signal-to-noise ratios of 3 and 10 were in the range of 0.16 to 0.91 and 0.52 to 3.0 ng/L, respectively. The polychlorinated biphenyl concentrations in environmental water samples were successfully determined using the developed method. PCB008 and PCB110 were 4.05 and 8.52 ng/L in Red-Star lake water (Hubei Province, China), respectively.

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