Dispersal and Transmission of Avian Paramyxovirus Serotype 4 among Wild Birds and Domestic Poultry

Yin, Renfu; Zhang, Pingze; Liu, Xinxin; Chen, Yanyu; Tao, Zhi‐Yong; Ai, Lili; Li, Junjiao; Yang, Yingying; Li, Mingxin; Xue, Cong; Qian, Jing; Wang, Xueli; Jing, Chen; Li, Yong; Xiong, Yanping; Zhang, Jun; Stoeger, Tobias; Bi, Yang; Chen, Jianjun; Ding, Zhuang

doi:10.3389/fcimb.2017.00212

Cited by 20 publications

(16 citation statements)

References 30 publications

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“…Surveillance data were also observed by researchers who performed similar monitoring researches of wild birds and domestic poultry and identified AAvV‐6 viruses (Shortridge, Alexander, & Collins, ; Sobolev et al., ), such as the isolate rate of AAvV‐6 in shorebirds was 2.4% in Germany during the year 2001–2002 (Hlinak et al., ) and in free‐living wild ducks was 0.76‰ in South Korea during the winter season (November to February) between 2010 and 2014 (Choi et al., ). However, our current data clearly indicate that AAvV‐6 is a lower isolated virus (the isolate rate was 0.1‱, 1/9, 872) in wild birds in China from the year 2013–2017 as compared with other AAvVs, such as AAvV‐1 and ‐4 (Yin et al., ; Zhang et al., ). Meanwhile, no AAvV‐6 isolate was obtained from domestic poultry.…”

Section: Resultsmentioning

confidence: 49%

“…Presence and identification of AAvV‐6 in each individual collected specimen was performed through allantoic cavities inoculation of 9 to 10‐day‐old specific‐pathogen‐free (SPF) chicken embryos (Merial, Beijing, China) (Kim, King, Suarez, Wong, & Afonso, ; Yin et al., ). The presence of the AAvV‐6 in allantoic fluid was identified by RT‐PCR and sequencing for paramyxoviruses (Tong, Chern, Li, Pallansch, & Anderson, ).…”

Section: Methodsmentioning

confidence: 99%

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Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China

Chen

Ding

Liu

et al. 2018

Transbound Emerg Dis

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Up to now only nine whole genome sequences of avian avulavirus 6 (AAvV-6) had been documented in the world since the first discovery of AAvV-6 (AAvV-6/duck/HongKong/18/199/77) at a domestic duck in 1977 from Hong Kong of China. Very limited information is known about the regularities of transmission, genetic and biological characteristics of AAvV-6 because of the lower isolation rate and mild losses for poultry industry. To better further explore the relationships among above factors, an AAvV-6 epidemiological surveillance of domestic poultry and wild birds in six provinces of China suspected of sites of inter-species transmission and being intercontinental flyways during the year 2013-2017 was conducted. Therefore, 9,872 faecal samples from wild birds and 1,642 cloacal and tracheal swab samples from clinically healthy poultry of live bird market (LBM) were collected respectively. However, only one novel hemagglutination-negative AAvV-6 isolate (AAvV-6/mallard/Hubei/2015) was isolated from a fresh faecal sample obtained from mallard at a wetland of Hubei province. Sequencing and phylogenetic analyses of this AAvV-6 isolate (AAvV-6/mallard/Hubei/2015) indicated that this isolate grouping to genotype I were epidemiological intercontinentally linked with viruses from the wild birds in Europe and America. Meanwhile, at least two genotypes (I and II) are existed within serotype AAvV-6. In additional, this novel hemagglutination-negative AAvV-6 isolate in chicken embryos restored its hemagglutination when pre-treated with trypsin. These findings, together with data from other AAvV-6, suggest potential epidemiological intercontinental spreads among AAvV-6 transmission by wild migratory birds, and reveal potential threats to wild birds and domestic poultry worldwide.

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Section: Resultsmentioning

confidence: 49%

Section: Methodsmentioning

confidence: 99%

Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China

Chen

Ding

Liu

et al. 2018

Transbound Emerg Dis

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“…During the years from 2013 to 2018, both cloacal and oropharyngeal swab samples from clinically healthy domestic poultry from the live bird market ( n = 3974) and fresh fecal samples from migratory birds in wetlands ( n = 14,909) were collected from six provinces of China, including two provinces in Central China (Hubei and Hunan), one in East China (Anhui), one in Northeast China (Jilin), one in Northwest China (Qinghai) and one in North China (Neimenggu), as part of both the avian influenza virus (AIV) and NDV surveillance program [18,19,20,21]. The detailed information on sample collection, transportation, and handing as described in our previous study [18,19]. In brief, samples were collected using sterile swabs and placed into viral transport media containing 2 mg/mL streptomycin, 50 U/mL nystatin, 50 µg/mL gentamycin, 2000 U/mL penicillin, and 0.5% bovine serum albumin.…”

Section: Methodsmentioning

confidence: 99%

The Emergence of Avian Orthoavulavirus 13 in Wild Migratory Waterfowl in China Revealed the Existence of Diversified Trailer Region Sequences and HN Gene Lengths within this Serotype

Fei

Liu

et al. 2019

Viruses

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Avian orthoavulavirus 13 (AOAV-13), also named avian paramyxovirus 13 (APMV-13), has been found sporadically in wild birds around the world ever since the discovery of AOAV-13 (AOAV-13/wild goose/Shimane/67/2000) in a wild goose from Japan in 2000. However, there are no reports of AOAV-13 in China. In the present study, a novel AOAV-13 virus (AOAV-13/wild goose/China/Hubei/V93-1/2015), isolated from a wild migratory waterfowl in a wetland of Hubei province of China, during active surveillance from 2013 to 2018, was biologically and genetically characterized. Phylogenetic analyses demonstrated a very close genetic relationship among all AOAV-13 strains, as revealed by very few genetic variations. Moreover, pathogenicity tests indicated that the V93-1 strain is a low virulent virus for chickens. However, the genome of the V93-1 virus was found to be 16,158 nucleotides (nt) in length, which is 12 nt or 162 nt longer than the other AOAV-13 strains that have been reported to date. The length difference of 12 nt in strain V93-1 is due to the existence of three repeats of the conserved sequence, “AAAAAT”, in the 5′-end trailer of the genome. Moreover, the HN gene of the V93-1 virus is 2,070 nt in size, encoding 610 aa, which is the same size as the AOAV-13 strain from Japan, whereas that of two strains from Ukraine and Kazakhstan are 2,080 nt in length, encoding 579 aa. We describe a novel AOAV-13 in migratory waterfowl in China, which suggests that diversified trailer region sequences and HN gene lengths exist within serotype AOAV-13, and highlight the need for its constant surveillance in poultry from live animal markets, and especially migratory birds.

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“…Last, the presence of APMV antibodies (other than NDV) in commercial poultry may undermine the efficacy of chimeric NDV vectors. APMV-2 to -15 and APMV-17 were mainly isolated from a variety of wild birds worldwide and APMV transmission between wild birds and domestic poultry was reported [ 139 , 140 ]. A serosurveillance of commercial poultry farms in USA showed the presence of antibodies to APMV-1 to -9 except for APMV-5 [ 141 ], which may interfere with the effectiveness of chimeric APMV vectors.…”

Section: Efforts To Circumvent the Interference Of Mda With The Ndmentioning

confidence: 99%

Newcastle Disease Virus as a Vaccine Vector for 20 Years: A Focus on Maternally Derived Antibody Interference

Cao

et al. 2020

Vaccines

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It has been 20 years since Newcastle disease virus (NDV) was first used as a vector. The past two decades have witnessed remarkable progress in vaccine generation based on the NDV vector and optimization of the vector. Protective antigens of a variety of pathogens have been expressed in the NDV vector to generate novel vaccines for animals and humans, highlighting a great potential of NDV as a vaccine vector. More importantly, the research work also unveils a major problem restraining the NDV vector vaccines in poultry, i.e., the interference from maternally derived antibody (MDA). Although many efforts have been taken to overcome MDA interference, a lack of understanding of the mechanism of vaccination inhibition by MDA in poultry still hinders vaccine improvement. In this review, we outline the history of NDV as a vaccine vector by highlighting some milestones. The recent advances in the development of NDV-vectored vaccines or therapeutics for animals and humans are discussed. Particularly, we focus on the mechanisms and hypotheses of vaccination inhibition by MDA and the efforts to circumvent MDA interference with the NDV vector vaccines. Perspectives to fill the gap of understanding concerning the mechanism of MDA interference in poultry and to improve the NDV vector vaccines are also proposed.

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Dispersal and Transmission of Avian Paramyxovirus Serotype 4 among Wild Birds and Domestic Poultry

Cited by 20 publications

References 30 publications

Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China

Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China

The Emergence of Avian Orthoavulavirus 13 in Wild Migratory Waterfowl in China Revealed the Existence of Diversified Trailer Region Sequences and HN Gene Lengths within this Serotype

Newcastle Disease Virus as a Vaccine Vector for 20 Years: A Focus on Maternally Derived Antibody Interference

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