Disparities in adversity among children with autism spectrum disorder: a population‐based study

Berg, Kristin; Shiu, Cheng Shi; Acharya, Kruti; Stolbach, Bradley; Msall, Michael E.

doi:10.1111/dmcn.13161

Cited by 108 publications

(97 citation statements)

References 22 publications

(80 reference statements)

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“…Primary outcomes were having ≥2 ACEs and ≥4 ACEs. These outcomes were selected given that a quarter of the NCHS sample experienced ≥2 ACEs and research suggesting that ≥4 ACEs reflect a clinically meaningful threshold (Berg et al 2016). We chose to consider ACEs that occur for children of all races and ethnicities.…”

Section: Methodsmentioning

confidence: 99%

“…The findings of Berg et al (2016) and Rigles (2016) provide compelling and novel evidence of disparities in both ACEs and mental health outcomes in children with and without ASD. However, they do not fully illustrate how the varied clinical profiles of children with ASD may moderate or contribute to these relationships.…”

Section: Introductionmentioning

confidence: 95%

“…Research suggests that individuals with autism spectrum disorder (ASD) experience a greater number of adverse childhood experiences (ACEs; Felitti et al, 1998) that may compromise their chances for optimal physical and mental health outcomes (Berg et al, 2016; Rigles, 2016). Using data from the 2011–2012 National Survey of Children’s Health (NSCH), Berg et al (2016) found that a caregiver-reported ASD diagnosis was associated with higher probability of experiencing 1–3 and ≥ 4 ACEs in US children, after controlling for poverty and residential disadvantage.…”

Section: Introductionmentioning

confidence: 99%

“…Using data from the 2011–2012 National Survey of Children’s Health (NSCH), Berg et al (2016) found that a caregiver-reported ASD diagnosis was associated with higher probability of experiencing 1–3 and ≥ 4 ACEs in US children, after controlling for poverty and residential disadvantage. Building upon these findings, Rigles (2016) found ACEs to be negatively associated with health and mental health, but not resiliency (a protective factor that can be eroded by ACEs; Tiet et al, 1998), in children with ASD in the NSCH.…”

Section: Introductionmentioning

confidence: 99%

“…Though Berg et al (2016) and Rigles (2016) included poverty as a covariate in their regression models, this approach may obscure a differential relationship between ACEs and ASD by poverty level (e.g., a vulnerability to ACEs in children with ASD and financial insecurity), a pattern discernable by stratification.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Brief Report: Examining the Association of Autism and Adverse Childhood Experiences in the National Survey of Children’s Health: The Important Role of Income and Co-occurring Mental Health Conditions

Kerns

Newschaffer

Berkowitz

et al. 2017

J Autism Dev Disord

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Adverse childhood experiences (ACEs) are risk factors for mental and physical illness and more likely to occur for children with autism spectrum disorder (ASD). The present study aimed to clarify the contribution of poverty, intellectual disability and mental health conditions to this disparity. Data on child and family characteristics, mental health conditions and ACEs were analyzed in 67,067 youth from the 2011–2012 National Survey of Children’s Health. In an income-stratified sample, the association of ASD and ACEs was greater for lower income children and significantly diminished after controlling for child mental health conditions, but not intellectual disability. Findings suggest that the association of ACEs and ASD is moderated by family income and contingent on co-occurring mental health conditions.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Brief Report: Examining the Association of Autism and Adverse Childhood Experiences in the National Survey of Children’s Health: The Important Role of Income and Co-occurring Mental Health Conditions

Kerns

Newschaffer

Berkowitz

et al. 2017

J Autism Dev Disord

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Adverse childhood experiences and the development of Down syndrome regression disorder

Wang

Patel

Sannar

et al. 2023

American J of Med Genetics Pt A

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Down syndrome regression disorder (DSRD) is a clinical symptom cluster of acute or subacute neurocognitive regression in otherwise health persons with Down syndrome. The objective of this study was to evaluate if adverse childhood experiences (ACEs) were more prevalent in children with DSRD than those with DS alone. A survey-based, cohort-based study was performed. Caregivers of individuals with DSRD with onset of symptoms between age 10 and 30 years and DS alone were administered the ACEs questionnaire via an online REDCap survey. A total of 159 responses were collected after excluding incomplete surveys and those not meeting criteria for DSRD. Individuals with DSRD were not more likely to experienceACEs (p = 0.18, 95% confidence interval [CI]: 0.43-1.17). In those with ACEs prior to the onset of symptoms, the median time prior was 7 months (interquartile range: 5-10). Individuals with DSRD were more likely to report three or more ACEs (52, 33%) compared to those with DS alone (39, 22%) (p = 0.02, 95% CI: 1.08-2.87).Exposure to ACEs were not predictive of response to particular therapeutic interventions although those with multiple ACEs 3 months prior to the onset of symptoms was associated with lower response rates to benzodiazepines and immunotherapy

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The association of adverse life events and parental mental health with emotional and behavioral outcomes in young adults with autism spectrum disorder

et al. 2021

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People with autism spectrum disorder (ASD) are at increased risk of developing co‐occurring mental health difficulties across the lifespan. Exposure to adverse life events and parental mental health difficulties are known risk factors for developing a range of mental health difficulties. This study investigates the association of adverse life events, parental stress and mental health with emotional and behavioral problems in young adults with ASD. One hundred and fifteen young adults with ASD derived from a population‐based longitudinal study were assessed at three time‐points (12‐, 16‐, and 23‐year) on questionnaire measures of emotional and behavioral problems. Parent‐reported exposure to adverse life events and parental stress/mental health were measured at age 23. We used structural equation modeling to investigate the stability of emotional and behavioral problems over time, and the association between adverse life events and parental stress and mental health and emotional and behavioral outcomes at 23‐year. Our results indicate that exposure to adverse life events was significantly associated with increased emotional and behavioral problems in young adults with ASD, while controlling for symptoms in childhood and adolescence. Higher reported parental stress and mental health difficulties were associated with a higher frequency of behavioral, but not emotional problems, and did not mediate the impact of adverse life events. These results suggest that child and adolescent emotional and behavioral problems, exposure to life events and parent stress and mental health are independently associated, to differing degrees, with emotional or behavioral outcomes in early adulthood. Lay Summary People with autism experience high rates of mental health difficulties throughout childhood and into adult life. Adverse life events and parental stress and mental health may contribute to poor mental health in adulthood. We used data at three time points (12‐, 16‐, and 23‐year) to understand how these factors relate to symptoms at 23‐year. We found that emotional and behavioral problems in childhood, adverse life events and parent mental health were all associated with increased emotional and behavioral problems in adulthood.

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Disparities in adversity among children with autism spectrum disorder: a population‐based study

Cited by 108 publications

References 22 publications

Brief Report: Examining the Association of Autism and Adverse Childhood Experiences in the National Survey of Children’s Health: The Important Role of Income and Co-occurring Mental Health Conditions

Brief Report: Examining the Association of Autism and Adverse Childhood Experiences in the National Survey of Children’s Health: The Important Role of Income and Co-occurring Mental Health Conditions

Adverse childhood experiences and the development of Down syndrome regression disorder

The association of adverse life events and parental mental health with emotional and behavioral outcomes in young adults with autism spectrum disorder

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