Disparate micro-mechanical behaviors of adjacent bone lamellae through in situ SEM micropillar compression

Graphene Oxide-Induced Substantial Strengthening of High-Entropy Alloy Revealed by Micropillar Compression and Molecular Dynamics Simulation

“…The noteworthy point here is that the stress-strain responses obtained by the micropillar compression testing were proven significantly different from the macroscopic mechanical testing. As previously mentioned, micropillar compression testing, size effect, and stress burst were more obvious at a small scale [16,17]. Combining the observation of the morphologies of deformed micropillars, researchers could quantitatively estimate the relationship between plastic deformation mechanisms and micromorphology.…”

​Investigating the Post-Yield Behavior of Mineralized Bone Fibril Arrays Using a 3d Non-Linear finite Element Unit-Cell Model

“…Maghsoudi-Ganjeh et al evaluated the mechanical behavior and failure mechanism of bone at the sub-lamellar level under compressive and tensile loading. They presented a 2D model in which the HA platelet was added to the collagen matrix with a layer of water and the mineral crystals bonded to each other with a thin layer of NCPs, forming the MCF and EFM, respectively (Maghsoudi-Ganjeh et al, 2019). The failure mechanism in compression began with relative sliding between HA crystals, and delamination between MCF and EFM and local buckling of MCF occurred as a result of shear bands.…”

“…The elastic modulus, yield stress, and failure mechanism of bone ECM were evaluated under monotonic and cyclic compression tests in both axial and transverse directions. Using micropillar compression tests, Ma et al (2021) evaluated the mechanical behavior of bovine bone samples fabricated from three adjacent E. Alizadeh et al layers of single osteons. Using the proposed deformation theory, the effect of collagen fibril orientation on the mechanical behavior of the micropillar was investigated.…”

In Situ Bending Reveals Simultaneous Enhancements of Strength and Ductility of Cortical and Cancellous Layers Induced by the Cartilage Layer

“…In addition, in situ biomechanical testing could simultaneously obtain the morphological changes and the mechanical responses of composite bone structures, , which could be considered as effective approach to reveal the real-time interface behaviors. Meanwhile, Raman spectrum analysis of stress condition could also be used to obtain the stress difference at various micro regions of composite bone structure through the calculation of scattering frequency shift, which would provide direct evidence to further reveal the effect of cartilage on bone mechanics.…”

“…1,5 The existing investigations on the mechanical properties of cartilage and cortical layer mainly focused on the independent performances, including the toughness, friction, and wear properties of cartilage, 6 crack propagation path, 7 distribution of surface hardness and Young's modulus, 8 and strength and toughness of the cortical layer at different scales. 9,10 For instance, Fan et al studied the deviation rate between natural knee cartilage and polyvinyl alcohol hydrogel artificial cartilage under different compression conditions, 11 Tertuliano et al prepared several pillars with various diameters to investigate the size effect-induced brittle-to-ductile transition of the cortical layer. 12 Our previous studies also proposed a prediction approach of cross section fracture path of the cortical layer through establishment of nanoindentation array 8 and investigated the mechanical properties of the cortical layer related to temperature and orientation of Haversian canals.…”