Disparate effects of antihypertensive drugs on large artery distensibility and compliance in hypertension

Bortel, L.M.A.B. Van; Kool, M. J. F.; Spek, Janneke J.

doi:10.1016/s0002-9149(99)80504-9

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Structural Changes With Age1

Vascular System and Endothelium1

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Cited by 15 publications

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“…A number of other medications may improve arterial distensibility independently of their effects on blood pressure. The nitrates, angiotensin‐converting enzyme (ACE) inhibitors, and calcium channel antagonists, have been shown to have favorable effects on arterial compliance, suggesting that these medications can have an impact on arterial stiffness 7 , 22–24,27 , 28 . Dietary measures, including salt restriction, can lower arterial stiffness in certain salt‐sensitive individuals 2,9 .…”

Section: Structural Changes With Agementioning

confidence: 99%

“…The nitrates, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel antagonists, have been shown to have favorable effects on arterial compliance, suggesting that these medications can have an impact on arterial stiffness. 7,[22][23][24]27,28 Dietary measures, including salt restriction, can lower arterial stiffness in certain salt-sensitive individuals. 2,9 However, caution must be employed, as most elderly persons have a reduced capacity for sodium retention and osmotic drive for thirst, and are thus predisposed to developing serious dehydration and/or hyponatremia.…”

Section: Vascular System and Endotheliummentioning

confidence: 99%

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