Disorders of Granulopoiesis and Granulocyte Function

Laurence, Arian; Chowdary, Pratima; Ancliff, Philip

doi:10.1002/9780470987001.ch14

Cited by 1 publication

(1 citation statement)

References 167 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients with hemoglobin values of less than 10.5 mg/dL in those younger than 6 years old, 11 mg/dL in those 6-11 years of age, 12 mg/dL in females older than 12 years of age, and 13 mg/dL in males older than 12 years of age were considered anemic (15). Iron deficiency anemia was defined as microcytic anemia with a low mean corpuscular volume and a high red cell distribution width (16). Leukopenia was defined as a white blood cell counts of less than 4000 mm 3 in the complete blood count and neutropenia as an absolute neutrophil count of less than 1500 mm 3 .…”

Section: Methodsmentioning

confidence: 99%

The hematologic manifestations of pediatric celiac disease at the time ofdiagnosis and efficiency of gluten-free diet

Çatal¹,

Topal²,

Ermiştekin³

et al. 2015

Turk J Med Sci

View full text Add to dashboard Cite

Background/aim: To determine the hematologic manifestations at the time of diagnosis of celiac disease in children and the effects of a gluten-free diet on hematologic signs upon follow-up. Materials and methods:The records of patients with celiac disease who received a follow up examination at the Pediatric Gastroenterology Clinic between June 2006 and June 2013 were retrospectively examined.Results: Ninety-one patients were included in the study. The mean age at diagnosis was 8.1 ± 4.21 years and 59 patients (64.8%) were female. Thirty-two patients (35.2%) had hematologic signs at the time of diagnosis. Anemia (24.2%) was the most common hematologic sign, followed by thrombocytosis (16.5%) and leukopenia (4.4%). The tTG IgA titers were screened in 80 of the 91 patients during diagnosis. Follow-up examinations found that remission for anemia (P = 0.017), thrombocytosis (P = 0.039), and decreases in tTG IgA titers (P = 0.034) were more prominent in patients who had followed a strict gluten-free diet. Conclusion:Approximately one-third of the celiac disease patients had hematologic manifestations at the time of diagnosis. Remission in hematologic signs and decrease in tTG IgA titers were more prominent in patients who had adhered to a gluten-free diet.

show abstract

Section: Methodsmentioning

confidence: 99%