Disorders of Facial Hyperpigmentation

Syder, Nicole; Quarshie, Claudia; Elbuluk, Nada

doi:10.1016/j.det.2023.02.005

Cited by 5 publications

(3 citation statements)

References 72 publications

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“…However, overproduction and buildup of melanin can lead to various skin pigment irregularities, such as solar lentigines (SL), flat seborrheic keratosis (SK), melasma, freckles, and post‐inflammatory hyperpigmentation 1,2 . Typically, these pigmentation disorders manifest between the ages of 20 to 40, occurring more frequently in individuals with Fitzpatrick skin types III or IV 3 . Notably, among Asian women, pigmentary irregularities appear with increased severity and at an earlier life stage compared to French women 4 .…”

Section: Introductionmentioning

confidence: 99%

“… 1 , 2 Typically, these pigmentation disorders manifest between the ages of 20 to 40, occurring more frequently in individuals with Fitzpatrick skin types III or IV. 3 Notably, among Asian women, pigmentary irregularities appear with increased severity and at an earlier life stage compared to French women. 4 These irregularities are more significant indicators of aging than wrinkles for women of Asian origin, and raise important concerns, particularly regarding their quality of life.…”

Section: Introductionmentioning

confidence: 99%

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Skin dark spot mapping and evaluation of brightening product efficacy using Line‐field Confocal Optical Coherence Tomography (LC‐OCT)

Jdid,

Pedrazzani,

Lejeune

et al. 2024

Skin Research and Technology

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BackgroundFacial dark spots remain a significant challenge for the cosmetic industry, in terms of providing effective treatment. Using Line‐field Confocal Optical Coherence Tomography (LC‐OCT), we investigated the internal structural features of photo‐aging spot areas and evaluated the efficacy of a skin‐brightening cosmetic product.Materials and MethodsTwenty‐six Asian female volunteers, aged between 29 and 65 years, applied a cosmetic product on their entire face twice a day for 2 months. LC‐OCT was used to evaluate the dermal‐epidermal junction (DEJ) undulation and the volume density of melanin in the epidermis at D0 and D56. Skin brightening and redness were also assessed by photography (SkinCam).ResultsUsing LC‐OCT technology, various microscopic dark spot morphologies, spanning from minimally deformed DEJ to complex DEJ patterns, were identified. Dark spots characterized by slight deformities in the DEJ were predominantly observed in the youngest age group, while older volunteers displayed a wavier pattern. Furthermore, a total of 44 spots were monitored to evaluate the brightening product efficacy. A statistically significant reduction in melanin volumetric density of 7.3% in the spots and 12.3% in their surrounding area was observed after 56 days of product application. In line with these results, an analysis of color parameters using SkinCam reveals a significant increase in brightening and decrease in redness in both pigmented spots and the surrounding skin following application.ConclusionsLC‐OCT proves to be a valuable tool for in‐depth dark spots characterization and assessment of skin brightening products, enabling various applications in the field of dermatological sciences.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Skin dark spot mapping and evaluation of brightening product efficacy using Line‐field Confocal Optical Coherence Tomography (LC‐OCT)

Jdid,

Pedrazzani,

Lejeune

et al. 2024

Skin Research and Technology

View full text Add to dashboard Cite

show abstract

“…Melasma (ML) [ 1 ], naevus fusco-caeruleus zygomaticus (NZ) [ 2 ], freckles (FC) [ 3 ], cafe-au-lait spots (CS) [ 4 ], nevus of ota (NO) [ 5 ], and lentigo simplex (LS) [ 6 ] are common hyperpigmented skin diseases on the face that seriously affect the aesthetics and social activities of patients [ 7 ]. Medical doctors diagnose a disease mainly by integrating clinical symptoms, medical images, and laboratory test results [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Image classification and auxiliary diagnosis system for hyperpigmented skin diseases based on deep learning

Lu,

Tong,

et al. 2023

Heliyon

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Review of Fractional Nonablative Lasers for the Treatment of Dermatologic Conditions in Darker Skin Phototypes

Aggarwal,

Rossi,

Puyana

et al. 2024

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BACKGROUND Fractional nonablative lasers (NAFLs) have demonstrated efficacy and safety for treating dermatologic conditions in patients with darker skin phototypes. Nonablative lasers are preferred in darker skin tones due to lower risk of postinflammatory hyperpigmentation. OBJECTIVE This review aims to identify the ideal laser options and parameters for treating common dermatologic conditions in patients with skin types IV-VI. MATERIALS AND METHODS A comprehensive literature search was conducted on PubMed in May 2023. Of 1,065 articles were identified, and 40 articles met the inclusion criteria. The studies were classified based on design, dermatologic condition, and skin phototype of patients, and assigned levels of evidence according to the Modified Criteria of the Oxford Center of Evidence Based Medicine. RESULTS Strong level 1 evidence supports the treatment of melasma and atrophic scars using NAFL. Moderate level 2 evidence was found for using NAFL in acne vulgaris, striae, and skin rejuvenation; 45% of the studies examined skin types III-IV, 20% III-V, 7.5% II-IV, 5% II-V, 5% IV alone, and 2.5% I-IV. CONCLUSION Further research is needed to determine the optimal treatment modalities and parameters for skin types V and VI. Appropriate device selection and conservative treatment settings are crucial for optimizing outcomes and minimizing adverse events.

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Disorders of Facial Hyperpigmentation

Cited by 5 publications

References 72 publications

Skin dark spot mapping and evaluation of brightening product efficacy using Line‐field Confocal Optical Coherence Tomography (LC‐OCT)

Skin dark spot mapping and evaluation of brightening product efficacy using Line‐field Confocal Optical Coherence Tomography (LC‐OCT)

Image classification and auxiliary diagnosis system for hyperpigmented skin diseases based on deep learning

Review of Fractional Nonablative Lasers for the Treatment of Dermatologic Conditions in Darker Skin Phototypes

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