“…This information-theoretic approach to study interactions has found many applications to complex systems such as gene networks (e.g., [ 8 , 9 , 10 ]), interactive agents (e.g., [ 11 , 12 , 13 , 14 ]), or neural processing (e.g., [ 15 , 16 , 17 ]). More generally, the nature of the information contained in the inputs determines the complexity of extracting it [ 18 , 19 ], how robust it is to disrupt the system [ 20 ], or how input dimensionality can be reduced without information loss [ 21 , 22 ].…”