Diseases of the Veins and Arteries: Leg Ulcers

Mortimer, Peter; Burnand, K. G.

doi:10.1002/9780470750520.ch50

Cited by 13 publications

(21 citation statements)

References 275 publications

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“…1 Immunosuppressive therapy and vasodilators have not been shown to be useful. 2 Chemical or surgical sympathectomy has been reported to be useful in the treatment of Buerger's disease, 2 particularly in patients with a predominately vasospastic component of their Buerger's disease. 11 In combination with local wound care and medical therapy, bilateral video-assisted thoracoscopic sympathectomies were performed, with a clinical increase in digital blood flow.…”

Section: Discussionmentioning

confidence: 99%

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Painful digital infarction in a male smoker treated as Buerger's disease

2008

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A 40-year-old male smoker presented with a 3-week history of painful digital infarction involving the hands. Histology was unhelpful, showing lichen simplex chronicus. A provisional diagnosis of a vasculitic disease was made. Treatment included aspirin, azathioprine, iloprost, methylprednisolone, nifedipine and prednisolone. After failure of these treatments an alternative clinical diagnosis of Buerger's disease was made. Treatment was to advise the patient of the importance of continuing to abstain from smoking, to perform bilateral video-assisted thoracoscopic sympathectomies and to commence folate supplementation. This led to marked improvement of his symptoms and healing of the digital infarction.

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Section: Discussionmentioning

confidence: 99%

“…It is an inflammatory occlusive disorder affecting the small-to medium-sized arteries and veins of predominantly the upper limbs of male smokers aged between 25 and 40 years. 1,2 It can lead to ischaemia, ulceration, gangrene and limb loss. The elusive aetiology of this disease makes it difficult to diagnose and treat.…”

Section: Introductionmentioning

confidence: 99%

Painful digital infarction in a male smoker treated as Buerger's disease

2008

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“…The lesions are brown to plum red plaques, resembling Kaposi's sarcoma clinically, hence the name. [45]Pseudo-allergic reaction: The reaction is not substance-specific, and similar reactions may occur to unrelated compounds in the same individual, due to inhibition of cyclo-oxygenase pathway of arachidonic acid metabolism and reduction of PGE 2 , which is inhibitory for mast cell de-granulation. The severity of the reaction is related to the dose of the offending substance.…”

Section: Pseudo-conditions/diseasesmentioning

confidence: 99%

"Pseudo" nomenclature in dermatology: What′s in a name?

Ghosh

Jain

2013

Indian J Dermatol

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In the bewildering array of scientific nomenclature in the medical field, it is important to use correct terminology, know their aberrations and the reason behind a specific terminology. This paper is an attempt towards compiling all the pseudo-nomenclatures coined in dermatology, in order to make it easier to retain and recollect these pseudo names, signs, morphology, diseases, and conditions. It is also imperative to know the true entities that these pseudo names masquerade as, so as to understand the explanation for assigning the term ‘pseudo’ to these conditions. A total of 52 pseudo-terms have been compiled here in reference to dermatology. Most of these pseudo-nomenclatures were coined due to some clinical or histopathological resemblance to the true conditions, while some were premature conclusions drawn from a flawed understanding of the basic nature of the condition. Clear understanding of each of these terms and the explanation behind them being pseudo will enable a dermatologist to avoid misdiagnosis and needless confusion.

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“…History of recurrent epistaxis starting as early as during infancy, presence of numerous cutaneous and mucosal telangiectasia and repeated hemorrhagic episodes from multiple sites among several family members are the other clues to the diagnosis. [11] Expanded fungiform papillae of tongue due to presence of single, much dilated blood vessel in each of these (visible by capillary microscopy) is a diagnostic feature of this disorder. [11] Disorder of keratinization 'V'-shaped notch on the free edge of the nail plate [ Figure 2] along with alternate longitudinal red (erythronychia) and white (leukonychia) bands are the distinct features of Darier's disease.…”

Section: Nail Patella Syndromementioning

confidence: 99%

“…[11] Expanded fungiform papillae of tongue due to presence of single, much dilated blood vessel in each of these (visible by capillary microscopy) is a diagnostic feature of this disorder. [11] Disorder of keratinization 'V'-shaped notch on the free edge of the nail plate [ Figure 2] along with alternate longitudinal red (erythronychia) and white (leukonychia) bands are the distinct features of Darier's disease. Splinter hemorrhages may be associated.…”

Section: Nail Patella Syndromementioning

confidence: 99%

Nails: Diagnostic clue to genodermatoses

Inamadar¹,

Palit²

2012

Indian J Dermatol Venereol Leprol

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Nails are cutaneous appendages mostly involved in mechanical functions. However, nails may reflect presence of various systemic disorders evidenced by alteration of their shape, size, color or texture. Genodermatoses are multisystem disorders with cutaneous involvement. Many of the genodermatoses present with nail changes and some of these may be the clinical pointers to the diagnosis. Diagnostic clues to various genodermatoses derived from nail findings have been discussed.

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Diseases of the Veins and Arteries: Leg Ulcers

Cited by 13 publications

References 275 publications

Painful digital infarction in a male smoker treated as Buerger's disease

Painful digital infarction in a male smoker treated as Buerger's disease

"Pseudo" nomenclature in dermatology: What′s in a name?

Nails: Diagnostic clue to genodermatoses

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