Diseases of the Liver and Liver Failure

Mair, T. S.; Divers, Thomas J.

doi:10.1002/9781119063254.ch51

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2019

2023

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Cited by 2 publications

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“…In horses, hyperammonemia has been linked to clinical signs of encephalopathy without evidence of liver disease, which promotes the formation of Alzheimer's cells II [80]. It is also suggested that alteration of amino acid metabolism with upward regulation of aromatic amino acids and downward regulation of BCAA lead to direct neuronal inhibition secondary to effects on CNS.…”

Section: Other Conditionsmentioning

confidence: 99%

Clinical Aspects Related to Plasma Serotonin in the Horse

Ambrojo¹,

Poggi²,

Corzano³

2019

Serotonin

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Serotonin (5-HT) is a neurotransmitter that has important functions such as the physiological regulation of hemostasis, blood clotting, bone metabolism, cardiovascular growth, contractile activity and gastrointestinal motility, renal function, and stress and sexual behavior, among others. In this review, we consider the potential of 5-HT to contribute to the development of various pathological conditions, including metabolic, vascular, and nervous disorders in horses. The values of 5-HT in circulation are modified under common pathological conditions. Thus, laminitis, endotoxemia, surgical cramps, recurrent airway obstruction, Cushing's syndrome, central fatigue, and certain behavioral alterations such as stereotypes and other acute or chronic conditions can cause increased levels of 5-HT.

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Section: Other Conditionsmentioning

confidence: 99%