Disease spectrum of cervical lymphadenitis: Analysis based on ultrasound-guided core-needle gun biopsy

Song, Joon Young; Cheong, Hee Jin; Kee, Sae Yoon; Jacob, Louis; Sohn, Jang Wook; Kim, Jong Hun; Seo, Sungkyu; Kim, In Sun; Kim, Woo Joo

doi:10.1016/j.jinf.2007.06.004

Cited by 54 publications

(39 citation statements)

References 22 publications

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“…Because these diseases have quite different treatment regimens and clinical courses, it is important to differentiate them. 6 To our knowledge, this is the first study in which patterns of nodal necrosis on CT of KD and TL were analyzed objectively and quantitatively. Our results indicate that mild-to-moderate multiple necrotic foci with indistinct margins and higher necrosis attenuation indices (CTN and CTN/M) without calcification were statistically significant parameters in the differentiation of KD from TL.…”

Section: Discussionmentioning

confidence: 96%

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Kikuchi Disease: Differentiation from Tuberculous Lymphadenitis Based on Patterns of Nodal Necrosis on CT

Lee¹,

Yoo²,

Lee³

2011

AJNR Am J Neuroradiol

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Section: Discussionmentioning

confidence: 96%

“…5 Therefore, it is important to differentiate KD and TL to ensure appropriate treatment. 6 FNAB has been considered a diagnostic tool for KD and TL, but FNAB may not be the best solution to differentiate these diseases. The diagnostic accuracy of FNAB for KD was reported to be approximately 50%, possibly because of cytologic features overlapping those of TL.…”

mentioning

confidence: 99%

Kikuchi Disease: Differentiation from Tuberculous Lymphadenitis Based on Patterns of Nodal Necrosis on CT

Lee¹,

Yoo²,

Lee³

2011

AJNR Am J Neuroradiol

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“…To our knowledge, this is the first report of 18 F-FDG PET/ CT imaging of an infection caused by M. simiae in a human patient. 18 F-FDG PET/CT cannot differentiate among the different causes of necrotizing cervical lymphadenitis, which can be caused by different bacteria, including Mycobacterium tuberculosis, Mycobacterium avium intracellulare, Histoplasma capsulatum, Coccidioides immitis, Bartonella henselae, Francisella tularensis, Chlamydia trachomatis L2, Yersinia pseudotuberculosis and Yersinia enterocolitica; and nonbacterial causes such as viral pathogens (e.g., Herpes simplex, Parvovirus B19) [13][14][15], lymphoma, metastatic carcinoma [15] and Kikuchi disease [16][17][18]. However, in this case, the PET/CT whole-body scan was very helpful in identifying multiple sites of infection within the neck, in ruling out disseminated infection or infectious foci outside the neck, and in guiding biopsy and subsequent therapy.…”

Section: Discussionmentioning

confidence: 99%

Necrotizing Cervical Lymphadenitis Caused by Mycobacterium simiae in an HIV-Positive Patient: Imaging with 18F-FDG PET/CT

Makis

Rush

2011

Nucl Med Mol Imaging

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Mycobacterium simiae (M. simiae) is an opportunistic pathogen rarely associated with human disease, although in recent years M. simiae has been detected with increasing frequency in human immunodeficiency virus (HIV)-infected patients, usually causing disseminated infection with fever, diarrhea and weight loss. We report the case of an HIV-positive man, who was referred for an 18 F-FDG PET/CT to evaluate a solitary pulmonary nodule. The PET/CT showed incidental large necrotic cervical lymph nodes, compatible with necrotizing cervical lymphadenitis. Biopsy and culture of one of the affected lymph nodes were positive for M. simiae. We present the first report of 18 F-FDG PET/CT imaging of an infectious process caused by M. simiae in humans.Keywords Mycobacterium simiae . Necrotizing cervical lymphadenitis . Fluorodeoxyglucose . PET/CT . HIV Case ReportA 43-year-old HIV-positive man presented with a 2-week history of fevers and sore neck. His blood tests had shown: absolute CD4 count of 170 cells/ul (normal 420-1,980), absolute CD8 count of 966 cells/ul (normal 160-990), CD4/CD8 ratio 0.20 (normal 1.0-2.3) and WBC 13.3×10 9 (normal 4.0-11.0 ×10 9 , 62% neutrophils, 21% lymphocytes, 11% monocytes and 1% eosinophils). A contrast-enhanced CT of the neck showed mildly enlarged bilateral cervical lymph nodes at level 2A, the largest measuring 2.5 cm×2.0 cm on the left and 1.6 cm×1.5 cm on the right (Fig.

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“…Most patients with Kikuchi disease have a normal blood count [8], even though leukopenia is observed in 20-32% [9,21]. Atypical lymphocytes are reported in up to 25% of patients [18].…”

Section: Laboratory Testsmentioning

confidence: 99%

Kikuchi-Fujimoto disease: case report and review

Araújo‐Filho¹,

Freire²,

AraÃojo-Neto³

et al. 2017

Int J Med Rev Case Rep

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Objective:The development of associated febrile to lymphadenomegaly leads to several diagnostic hypotheses, among them the Kikushi-Fujimoto disease.Method:This review was set up by searching PubMed/Medline, Web of Science and Scopus database using the following key words: "Kikushi disease", "Kikuchi-Fujimoto disease", "histiocytic necrotizing", "lymphadenitis","lymphadenopathy". Results:We report a case in a young patient with a fever associated with the emergence of adenomegaly and weight loss in two months, associated with hepatosplenomegaly. In laboratory tests showed anaemia with erythrocyte sedimentation rate (ESH) and lactate dehydrogenase (LDH) test elevated, widened mediastinum, with bilateral pleural effusion. Conclusion:Excisional biopsy of supraclavicular lymph node showed Kikuchi-Fujimoto disease on microscopic examination. After histopathological confirmation, were other causes of febrile adenomegaly apart, starting dose corticosteroid immunosuppressive therapy.

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Disease spectrum of cervical lymphadenitis: Analysis based on ultrasound-guided core-needle gun biopsy

Cited by 54 publications

References 22 publications

Kikuchi Disease: Differentiation from Tuberculous Lymphadenitis Based on Patterns of Nodal Necrosis on CT

Kikuchi Disease: Differentiation from Tuberculous Lymphadenitis Based on Patterns of Nodal Necrosis on CT

Necrotizing Cervical Lymphadenitis Caused by Mycobacterium simiae in an HIV-Positive Patient: Imaging with 18F-FDG PET/CT

Kikuchi-Fujimoto disease: case report and review

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