Disease Recurrence Predictors for Patients With Head and Neck Squamous Cell Carcinoma

Abstract

Dis€ase Recurrsnce Predictors for Patients wilh Head and Neck Squamous Cell Carcinoma lnformationonreliablefactorslopredictpatientoutcomeisimportantfordecidinguponthebes treatment to increase loco-regional control, overall survival and quali'y oflife ofpalients with head and neck s,ruanous cell carcinoma ([NSCC). The objective of this studv was to invesligate the role of clinico-"]ir,oroni"uf o*ut.r." ns predictors ofdisease recurrence in patients with HNScc we studied fifty patients i"r," '.-t. .J"f'"g trcatment for primary HNSCC in Westmead Hospital between 2002-2004' tjnivariate anatysis was used-ro identi! any signrficant associalion between clinico-pathological param€lers and disease .".,it"r"". r, *u. .rto*.d that ieeip=0 0ost, cTNM stage (p=0 02), size of tumour (p=0 009) and positive iumour margin (p:0.002) prerticted the risk ofthe development ofdisease recunen€e ln agrcernen with other ,tua;", *" fiuni t6ur .or" tradilional factors influenced diseas€ recu.€nce. A longer follow'up study should beperformedloassessth€significanceofth€sefactorsonoverallsurvivalaswellasseparatestudl prolnl"ti" indi"otors fo. paie;ts wilh histologically negative lvmph node lndonesian loutnal of Dentisttv 2a06 Edisi Khusus KPPIKC XlV.362-367