Disease progression and survival in HIV-1-infected Africans in London

Amo, Julia del; Petruckevitch, Ann; Phillips, Andrew; Johnson, Anne M; Stephenson, Judith; Desmond, N; Hänscheid, Thomas; Low, Nicola; Newell, A; Obasi, Angela; Paine, Katie; Pym, Alexander S.; Theodore, C M; Cock, Kevin M. De

doi:10.1097/00002030-199810000-00013

Cited by 84 publications

(24 citation statements)

References 32 publications

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“…The majority of heterosexually acquired HIV infections in Europe are now in immigrants from high prevalence countries, who, like persons from ethnic minorities, present late to health services [116][117][118]. For example, in the UK, black Africans with HIV/AIDS, were more likely to present to outpatient clinics at an advanced stage of disease, but once diagnosed with HIV, their use of services was similar to that of the PLWHA who were not of black African origin [119][120][121][122][123][124][125].…”

Section: Services For the Socio-economically Disadvantaged Groupsmentioning

confidence: 99%

Health systems’ responses to 25 years of HIV in Europe: Inequities persist and challenges remain

2008

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Section: Services For the Socio-economically Disadvantaged Groupsmentioning

confidence: 99%

Health systems’ responses to 25 years of HIV in Europe: Inequities persist and challenges remain

2008

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“…These data are encouraging, because once the migrants are actually treated by the national health services in Europe, no differences can be observed in the intake of HAART, in progression to AIDS and in survival compared to native patients. 7,[14][15][16][17][18] The most commonly used regimen (44.8%) was composed of two nucleoside analogues and a non-nucleoside inhibitor that might reflect the clinicians apprehension about the use of more complex regimens; a once-daily regimen, however, was chosen only in a low percentage of cases (3%).…”

Section: Hiv-infected Immigrants and Access To Haart 603mentioning

confidence: 99%

Access to HAART in HIV-Infected Immigrants: A Retrospective Multicenter Italian Study

Saracino

El-Hamad²,

Prato³

et al. 2005

AIDS Patient Care and STDs

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Since 1996, AIDS has declined in the Italian population, but cases in foreign patients, including both recent immigrants and long-term residents, have increased from 3.9% in 1995-1996 to 15.4% in 2001-2002. This increase can only be partly explained by a higher migratory flow and might reflect a delayed access to health facilities and to antiretroviral therapy in migrants. We performed a survey for the year 2003 of HIV-infected immigrants to Italy from countries outside the European Union to verify which factors might influence a lack of access to highly active antiretroviral therapy (HAART). Italian centers of infectious diseases were requested to send sociodemographic and clinical data of HIV-infected immigrant patients. A total of 553 HIV-infected immigrants (49.9% women) were evaluated, representing 6.5% of all HIV-infected patients from these centers. The mean duration of residency in Italy was 6.6 +/- 5.0 years. The country of origin was Africa (64.5%), North and South America (24.2%), Eastern Europe (7.0%), and Asia (3.8%). A total of 407 of 553 patients (73.6%) were taking antiretroviral drugs at the time of screening. Females presented a younger age (p = 0.001), a lower frequency of Centers for Disease Control (CDC) stage B/C (p = 0.008) and a more frequent heterosexual exposure to HIV (p < 0.001), while no differences were observed for time of first positive serology (p = 0.7). CD4 cell count (p = 0.9) and log plasma HIV-RNA (p = 0.1). Characteristics of HAART patients were compared to those of nontreated patients, despite a CD4 cell count less than 350 cells/mm(3). No significant difference was found for gender, country of origin, risk factor, and years of Italian residence, while legal immigrants (p = 0.018) and registered in the National Health Service (p = 0.014) were significantly more likely to receive HAART compared to illegal immigrants.

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“…Once started on HAART, immunological and virological responses are equivalent in African and white UK patients (Frater et al ., 2002) and the response is at least as good in women as in men (Moore et al ., 2002). However, African patients appear to present to services at a more advanced stage of HIV disease compared to whites (Barry et al ., 2002;Del Amo et al ., 1998;Saul et al ., 2000). Several studies have shown a low self-perceived risk of HIV in African populations in the UK (Erwin et al ., 2002;Fenton et al ., 2002).…”

Section: Introductionmentioning

confidence: 99%

Women from Africa living with HIV in London: a descriptive study

2004

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There are no studies that have examined the particular needs and experiences of African women living with HIV in the UK at a time when they represent an increasingly large proportion of the UK HIV epidemic. This study explores the illness biographies and daily lives of HIV-positive African women receiving treatment in London. Sixty-two women from 11 African countries attending HIV specialist clinics in five London hospitals participated in self-completion questionnaires and in depth semi-structured interviews. Using a narrative approach, women were asked to talk about their HIV status in the broader context of their life history. Important differences exist within this group based mainly on nationality, income, education level and legal status in the UK. However, marked similarities also emerged which were related in part to their situation as migrants and were compounded by their illness. Stigma, both actual and perceived, had a profound impact on women's lives, making control of information about their situation a matter of acute concern. This had an effect on how women accessed health services and voluntary sector agencies. The resilience of women in dealing with difficulties in their lives was strengthened by religious belief. Such similarities and differences need to be properly understood by health and social care professionals if they are to offer the most appropriate care for this growing population of patients.

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Disease progression and survival in HIV-1-infected Africans in London

Cited by 84 publications

References 32 publications

Health systems’ responses to 25 years of HIV in Europe: Inequities persist and challenges remain

Health systems’ responses to 25 years of HIV in Europe: Inequities persist and challenges remain

Access to HAART in HIV-Infected Immigrants: A Retrospective Multicenter Italian Study

Women from Africa living with HIV in London: a descriptive study

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