Disease of the Liver in Regional Enteritis

Wl, Palmer; Jb, Kirsner; Mb, Goldgraber; Silvafuentes, S

doi:10.1097/00000441-196312000-00003

Cited by 14 publications

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“…Such evidence that is available has been based on histo logical examination of the liver which has often been provided at autopsy. It is thought that the commonest lesion is fatty change but chronic inflamma tion may be present and granulomata are occasionally found [5,8,9,11,22,24,32]. Rarely focal necrosis, cirrhosis, metastatic abscesses, amyloidosis and sclerosing cholangitis have been reported [1,29,33], Biochemical evidence of hepatic dysfunction is even harder to find in the literature and it is thought to be uncommon even in the presence of histolog ical lesions [15,22], However, Monto (20) and Dordal et al [9] showed that abnormal liver function tests were present in cases of Crohn's disease in whom there was a clinical impression of liver disturbance.…”

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The Incidence and Significance of Liver Dysfunction in Crohn’s Disease

Dyer¹,

Dawson²

1972

Digestion

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26% of 62 patients with Crohn’s disease had elevated serum levels of alkaline phosphatase and 58% of 38 patients showed impaired excretion of BSP; all the patients with hyperphosphatasaemia also showed increased BSP retention. There was no correlation of these tests with other indices of liver function which tended to be normal and no correlation with activity of the disease, duration of symptoms, age of the patient or the serum levels of albumin and cholesterol. Biochemical abnormalities due to liver dysfunction are common and should not be attributed to malabsorption.

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The Incidence and Significance of Liver Dysfunction in Crohn’s Disease

Dyer¹,

Dawson²

1972

Digestion

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An epidemiological study of regional enteritis in the gloucester area

Tresadern

Gear

Nicol

1973

British Journal of Surgery

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An epidemiological study has been made of regional enteritis in the Gloucester area during the period from 1 Jan., 1966, to 31 Dec., 1970. There were 19 cases in an average population of 253,000, giving an average incidence of new cases of 1.5 per 100,000 per year. There was a significant peak of cases in the 15–24 age‐group. The incidence in men was slightly higher than in women. There was a family history of ulcerative colitis in 2 cases. There were 3 cases of regional enteritis of the large bowel only, all occurring in women. Extensive large‐ and small‐bowel involvement occurred predominantly in the younger patients.

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Intrahepatische Cholangitis

Klinge¹

2000

Spezielle Pathologische Anatomie

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Disease of the Liver in Regional Enteritis

Cited by 14 publications

References 0 publications

The Incidence and Significance of Liver Dysfunction in Crohn’s Disease

The Incidence and Significance of Liver Dysfunction in Crohn’s Disease

An epidemiological study of regional enteritis in the gloucester area

Intrahepatische Cholangitis

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