Disease burden of pneumonia in Korean adults aged over 50 years stratified by age and underlying diseases

Lee, Jung Yeon; Yoo, Chul Gyu; Kim, Hyojin; Jung, Ki Suck; Yoo, Kwang Ha

doi:10.3904/kjim.2014.29.6.764

Cited by 16 publications

(10 citation statements)

References 25 publications

(50 reference statements)

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“…In addition, the proportion of infections of respiratory system in our study was greater than in other studies, including that from another study from Korea [19]. Increasing age is considered a risk factor for community-acquired pneumonia in high-income countries, and death rates due to pneumonia in elderly patients have increased over the past 30 years in Korea, in association with socioeconomic improvements and aging of the population [20]. In addition to the relatively older population, having collected patient data during the winter may be also a reason for the higher proportion of respiratory system infections in our study [21].…”

Section: Discussionmentioning

confidence: 61%

Characteristics, management and clinical outcomes of patients with sepsis: a multicenter cohort study in Korea

Jeon

et al. 2019

Acute Crit Care

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Background: Mortality rates associated with sepsis have increased progressively in Korea, but domestic epidemiologic data remain limited. The objective of this study was to investigate the characteristics, management and clinical outcomes of sepsis patients in Korea. Methods: This study is a multicenter retrospective cohort study. A total of 64,021 adult patients who visited an emergency department (ED) within one of the 19 participating hospitals during a 1-month period were screened for eligibility. Among these, patients diagnosed with sepsis based on the third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) were included in the study. Results: Using the Sepsis-3 criteria, 977 sepsis patients were identified, among which 36.5% presented with septic shock. The respiratory system (61.8%) was the most common site of infection. The pathogen involved was identified in 444 patients (45.5%) and multi-drug resistance (MDR) pathogens were isolated in 171 patients. Empiric antibiotic therapy was appropriate in 68.6% of patients, but the appropriateness was significantly reduced in infections associated with MDR pathogens as compared with non-MDR pathogens (58.8% vs. 76.0%, P < 0.001). Hospital mortality was 43.2% and 18.5% in sepsis patients with and without shock, respectively. Of the 703 patients who survived to discharge, 61.5% were discharged to home and 38.6% were transferred to other hospitals or facilities. Conclusions: This study found the prevalence of sepsis in adult patients visiting an ED in Korea was 1.5% (15.2/1,000 patients). Patients with sepsis, especially septic shock, had a high mortality and were often referred to step-down centers after acute and critical care.

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Section: Discussionmentioning

confidence: 61%

Characteristics, management and clinical outcomes of patients with sepsis: a multicenter cohort study in Korea

Jeon

et al. 2019

Acute Crit Care

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“…61 Although it is difficult to draw a conclusion from these limited data, countries with more advanced economy seem to show better outcomes with regard to pneumonia-specific mortality. Older age, [152][153][154] comorbidities, 27,154 nursing home residence, 27 and poor performance status 152,154 were associated with worse outcome, as in other regions of the world. A relatively small number of studies on the economic burden of CAP have been performed in the Asia-Pacific region.…”

Section: Clinical Outcomes and Socioeconomic Burden Of Cap In The Asimentioning

confidence: 88%

Community-Acquired Pneumonia in the Asia-Pacific Region

Song

Huh

Chung

2016

Semin Respir Crit Care Med

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Community-acquired pneumonia (CAP) is an important cause of mortality and morbidity worldwide. Aging population, dense urbanization, and poor access to health care make the Asia-Pacific region vulnerable to CAP. The high incidence of CAP poses a significant health and economic burden in this region. Common etiologic agents in other global regions including ,, ,, , and respiratory viruses are also the most prevalent pathogens in the Asia-Pacific region. But the higher incidence of and the presence of are unique to the region. The high prevalence of antimicrobial resistance in and has been raising the need for more prudent use of antibiotics. Emergence and spread of community-acquired methicillin-resistant deserve attention, while the risk has not reached significant level yet in cases of CAP. Given a clinical and socioeconomic importance of CAP, further effort to better understand the epidemiology and impact of CAP is warranted in the Asia-Pacific region.

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“…reported that age did not increase the cost, which might be attributed to the high mean age (70 ± 15 years) of their patients. Lee et al 27 . investigated the burden of CAP in adults aged ≥ 50 y in 11 hospitals in Korea and total per-capita medical fees were found to be higher in patients aged ≥ 65 y than in those aged <65 y (US$2,088 vs. US$1,701).…”

Section: Discussionmentioning

confidence: 99%

Burden of community-acquired pneumonia in adults over 18 y of age

Koşar

Alıcı²,

Hacibedel

et al. 2017

Human Vaccines & Immunotherapeutics

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This study aimed to determine the economic burden and affecting factors in adult community-acquired pneumonia (CAP) patients (≥ 18 years) by retrospectively evaluating the data of 2 centers in Istanbul province, Turkey. Data of outpatients and inpatients with CAP from January 2013 through June 2014 were evaluated. The numbers of laboratory analyses, imaging, hospitalization days, and specialist visits were multiplied by the relevant unit costs and the costs of the relevant items per patient were obtained. Total medication costs were calculated according to the duration of use and dosage. The mean age was 61.56 ± 17.87 y for the inpatients (n = 211; 48.6% female) and 53.78 ± 17.46 y for the outpatients (n = 208; 46.4% male). The total mean cost was €556.09 ± 1,004.77 for the inpatients and €51.16 ± 40.92 for the outpatients. In the inpatients, laboratory, medication, and hospitalization costs and total cost were significantly higher in those ≥ 65 y than in those <65 y. Besides the hospitalization duration, specialist visit, imaging, laboratory, medication, and hospitalization costs and total cost were significantly higher in those hospitalized more than once than in those hospitalized once. While the specialist visit cost was higher in the inpatients with comorbidities, the imaging cost was higher in the outpatients with comorbidities. CAP poses a higher cost in inpatients, elders, and individuals with comorbidities. Costs can be decreased by rational decisions about hospitalization and antibiotic use according to the recommendations of guidelines and authorities. Vaccination may decrease medical burden and contribute to economy by preventing the disease, especially in risk groups.

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Disease burden of pneumonia in Korean adults aged over 50 years stratified by age and underlying diseases

Cited by 16 publications

References 25 publications

Characteristics, management and clinical outcomes of patients with sepsis: a multicenter cohort study in Korea

Characteristics, management and clinical outcomes of patients with sepsis: a multicenter cohort study in Korea

Community-Acquired Pneumonia in the Asia-Pacific Region

Burden of community-acquired pneumonia in adults over 18 y of age

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