Disease burden and costs for patients with hip and knee osteoarthritis and chronic moderate-to-severe refractory pain on treatment with strong opioids in Spain

Sicras‐Mainar, Antoni; Rejas‐Gutiérrez, Javier; Negrín, Francisco Vargas; Tornero-Tornero, Juan Carlos

doi:10.1016/j.reuma.2022.02.004

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“…Guidelines for OA management recommend holistic assessment with a multidisciplinary approach that includes non-pharmacological, pharmacological, and surgical interventions (14)(15)(16)(17)(18). Importantly, there have been growing concerns for a number of years on the potential toxicity (especially in the US) and lack of benefits for opioids, which have been a staple in OA treatment recommendations (15,(19)(20)(21)(22).…”

Section: Introductionmentioning

confidence: 99%