Discussing HPV and oropharyngeal cancer in dental settings: gender and provider-type matter

Daley, Ellen M.; Thompson, Erika L.; Beckstead, Jason W.; Driscoll, Annelise Ydstebo; Vamos, Cheryl A.; Piepenbrink, Rumour; Desch, Jill; Merrell, Laura; Cayama, Morgan Richardson; Owens, Heather; Lovett, Sharonda M.

doi:10.1080/21645515.2021.1996809

Cited by 7 publications

(5 citation statements)

References 29 publications

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“…These studies support a growing body of research that demonstrates dentists and other oral healthcare providers are, in fact, willing to discuss HPV vaccination and participate in vaccine administration if they are given sufficient information about the increasing prevalence and risks of oral HPV infection, particularly among adolescent and young adult populations [44][45][46]. Given that some dental specialists, such as orthodontists, regularly visit with the at-risk groups identified in this study, including both pediatric (12-17 years old) and adult (18-24 years old) patients, novel pathways for increasing vaccine knowledge and awareness and countering misinformation may be developed to coincide with their frequent patient interactions [47,48].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Oral Human Papillomavirus Prevalence in Pediatric and Adult Patients within a Multi-Ethnic Clinic Population

et al. 2022

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Introduction: Human papillomavirus (HPV) encompasses a large family of oncogenic viruses responsible for increasing rates of both cervical and oral cancer, particularly among minority and low-income populations. Although this represents an increasingly significant public health risk, few studies have screened for oral HPV within Nevada. Based upon this information, the primary objective of this study was to provide a temporal analysis of oral HPV screening among a primarily low-income, minority patient population. Methods: This retrospective analysis was reviewed and approved by the Institutional Review Board (IRB). In brief, unstimulated saliva samples were previously obtained from clinical patient volunteers who provided informed consent and pediatric assent (if applicable). DNA was isolated and screened using spectrophotometry for quality (A260:A280 ratio > 1.70) and quantity (concentration > 100 ng). Validated qPCR primers were used to screen repository samples for high-risk HPV strains HPV16 and HPV18. Results: A total of N = 930 samples were identified for this study, which involved n = 555 samples from adults and n = 375 from pediatric patients treated between 2011 and 2019. A demographic analysis revealed nearly equal distribution between males and females with most derived from non-White (minority) patients. A qPCR screening revealed an overall increase in high-risk HPV of 3.17-fold from 5.7% in 2011 to 18.1% in 2019 and a coefficient of determination or R2 = 0.764, suggesting a strong, positive correlation between more recent sample years and HPV-positive results, which was observed among both pediatric (R2 = 0.671) and adult (R2 = 0.971) patients. In addition, although the average age among adult patients increased over time, a significant decrease was observed among pediatric patients from an average of 16.0 years to 14.81 years. Conclusions: These data suggest temporal changes and positive increases in the prevalence of oral HPV among both the pediatric and adult patient samples taken from this clinic population. These data are important as considerations are made regarding which HPV vaccination education and awareness programs are introduced and the specific populations most likely to benefit from these interventions.

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Section: Discussionmentioning

confidence: 99%

Assessment of Oral Human Papillomavirus Prevalence in Pediatric and Adult Patients within a Multi-Ethnic Clinic Population

et al. 2022

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“…The adapted survey included questions about patients' attitudes and acceptance of COVID‐19 and HPV vaccination, perceptions of dental care providers' role in COVID‐19 and HPV vaccination, and comfort in having a dental provider administer COVID‐19 and HPV vaccines (Table 1 ). Despite mixed evidence of acceptance from nondentist providers in the dental setting (Daley et al, 2021 ), the term “dental provider” was used throughout the survey due to wide comprehensibility and to maximize inclusivity.…”

Section: Methodsmentioning

confidence: 99%

“…In a series of studies, Daley and colleagues have found that dentists have mixed readiness to discuss vaccines. In addition, patients are more receptive to vaccine and risk discussions with dentists compared to allied dental health professionals and to receiving information from same‐gender providers (Daley et al, 2014 , 2021 ). Surveys by both Dean et al ( 2020 ) and Stull et al ( 2020 ) showed that a majority of parents were receptive to receiving HPV‐related information from dental professionals and would allow their child to receive the HPV vaccine from their dentist, while a study by Lazalde et al ( 2018 ) found that only one‐quarter of parents were comfortable with dentists administering the HPV vaccine.…”

Section: Introductionmentioning

confidence: 99%

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Oral healthcare providers play a vital role in vaccination efforts: Patient perspectives

Steinbaum,

Jagannath,

Seymour

et al. 2023

Clinical & Exp Dental Res

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ObjectivesHuman papillomavirus (HPV) is associated with 70% of oropharyngeal squamous cell carcinomas. Coronavirus disease 2019 (COVID‐19) is the infectious cause of a global pandemic that killed millions worldwide. Effective vaccinations exist against both diseases, but patient acceptance remains a challenge. The objective of this study was to assess patients' attitudes toward oral healthcare providers' (OHCPs) roles in HPV and COVID‐19 vaccinations.MethodsA cross‐sectional survey of young adult patients was distributed in Philadelphia, PA, between April and June 2021. The survey assessed knowledge and attitudes around OHCPs serving various roles in COVID‐19 and HPV vaccination.ResultsNearly 70% of 163 respondents would accept the recommendation for a COVID‐19 vaccine from an OHCP, while 56% would for HPV. Those previously vaccinated against COVID‐19 were more comfortable discussing COVID‐19 vaccines (92%, p < .001) or HPV vaccines (76%, p < .001) with OHCPs compared to those who were unvaccinated against COVID‐19. African American/Black patients were less comfortable discussing vaccines, irrespective of vaccination status.ConclusionsOHCP can play a vital role in increasing the overall COVID‐19 and HPV vaccination status of the public, as demonstrated by the high acceptance of dental involvement in both vaccine campaigns. Racial disparity in vaccination attitude is a public health challenge that needs to be addressed.

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“…In addition, there is also emerging evidence of possible oropharyngeal cancer prevention with the use of HPV vaccine ( 44 ). It should be noted that the vaccine is approved to prevent HPV-related cervical and anal precancer and cancer, but it is not approved to prevent HPV-related oral cancer ( 45 ).…”

Section: Hpv Vaccinationmentioning

confidence: 99%

Human papillomavirus infection-related cancer risk for kidney transplant recipients during adult life can be reduced by vaccination during childhood and adolescence

Nailescu

Shew

2022

Front. Pediatr.

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Malignancies are found between the first three reasons of mortality in pediatric and adult kidney transplant recipients, who overall have disproportionately higher rates of cancer compared to the general population, including human papillomavirus (HPV)-related genital, anal and oropharynx region cancers. Therefore, preventing HPV in this patient population is extremely important. HPV-vaccine was demonstrated to prevent HPV infection in individuals with intact immune systems. In addition, recent data reported less precancerous HPV lesions and cervical cancers with use of HPV vaccine. Since HPV is a sexually transmitted virus that is typically acquired shortly after the onset of sexual activity, it is best to administer the HPV vaccine immunization prior to the onset of sexual activity. This article reviews the epidemiology and pathophysiology of the HPV infection, as well as its role in the development of HPV-related pre-cancerous lesions and cancers in both general population and kidney transplant recipients. The focus is on the most effective primary prophylactic strategy, which is the HPV vaccination. The particularities of HPV vaccination strategies in kidney transplant recipients are compared to the general population. In addition, the article analyzes the various causes of suboptimal HPV immunization rates in kidney transplant candidates and recipients and discusses vaccination optimization strategies that can be applied during childhood and adolescence to reduce the burden of HPV-related disease states and cancer among adult kidney transplant recipients.

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Discussing HPV and oropharyngeal cancer in dental settings: gender and provider-type matter

Cited by 7 publications

References 29 publications

Assessment of Oral Human Papillomavirus Prevalence in Pediatric and Adult Patients within a Multi-Ethnic Clinic Population

Assessment of Oral Human Papillomavirus Prevalence in Pediatric and Adult Patients within a Multi-Ethnic Clinic Population

Oral healthcare providers play a vital role in vaccination efforts: Patient perspectives

Human papillomavirus infection-related cancer risk for kidney transplant recipients during adult life can be reduced by vaccination during childhood and adolescence

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