2018
DOI: 10.1101/199471
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Discrimination of Gram-Positive versus Gram-Negative Bacteria by the Social AmoebaDictyostelium discoideum

Abstract: 13Professional phagocytes detect, pursue, engulf, and kill bacteria. While all professional 14 phagocytes use chemotaxis to locate bacteria, little is known about whether they can 15 discriminate among them, responding preferentially to some bacteria over others. Here we 16 examine the chemotaxis of the soil amoeba and professional phagocyte Dictyostelium 17 discoideum in assays where amoebae were presented with a paired choice of different bacteria. 18We observed variation in the extent to which they pursue d… Show more

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