“…In zebrafish, for example, benzodiazepines have been shown to affect a plethora of anxiety-like behaviors, from bottom-dwelling (Bencan et al, 2009;Egan et al, 2009) and dark preference (Maximino et al, 2010(Maximino et al, , 2011 to shoal cohesion (Gebauer et al, 2011) and cocaine withdrawal-induced anxiety (López-Patiño et al, 2008). Likewise, benzodiazepines decrease tonic immobility duration and the following freezing and explosive behavior in a defensive behavior battery in the wall lizard (Tropidurus oreadicus), and also increase exploratory behavior in the same test (Maximino et al, 2014). In the separation stress paradigm, benzodiazepines attenuate separation stress-induced distress vocalizations in chicks in the anxiety phase, but not in the depression phase (Warnick et al, 2009).…”