Discriminating malaria and dengue fever in endemic areas: Clinical, biochemical and radiological criteria

Jain, Vineet; Khan, Afreen; Garg, Richa; Chopra, Arushi; Gaur, Diksha; Kashyap, Varun Kumar; Kohli, Sunil; Bajaj, Kanupriya

doi:10.1016/j.cegh.2020.04.014

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Dengue fever is currently diagnosed in the laboratory either directly by detecting viral components [non-structural glycoprotein-1 (NS1) antigen] in serum or indirectly by measuring antibodies (IgM). Both can cause life-threatening complications, therefore they must be detected early and precisely to allow for prompt treatment [11] . The purpose of this study was to determine the prevalence of both Malaria and Dengue fever as well as to link the severity of both illnesses to symptoms and hematological indicators.…”

Section: Introductionmentioning

confidence: 99%

Distribution and burden of malaria and dengue infections in a tertiary care hospital

Sharma,

Bisht,

Jain

et al. 2024

Int. J. Mosq. Res.

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Introduction: Malaria and Dengue are two vector borne diseases having gained a major concerns worldwide, particularly in tropical and subtropical region owing to their recurring outbreaks. Mosquito bite is considered to be the major cause they are transmitted to human by the bite of mosquito and cause different hematological manifestation. Aim: To compare the laboratory features and outcome of mono-infection or co-infection with both Malaria and Dengue infections. Materials and Methods: 256 suspected patients were tested for Malaria and Dengue infections. Serological diagnosis of dengue was done using rapid dengue duo kit which detects Ns1, IgM and IgG. Malarial parasite were identified by peripheral blood smear (thick and thin), rapid test were performed by Sure Test Malaria PF/PV HRP2/pLdh Combo kit which detects plasmodium falciparum and plasmodium vivax by using human blood. Results: Of the 256 cases, most affected age group was 19-35 years (77%) and the less affected age group was >56 years (23%) while male and female ratio is 1:1. Of the 256 cases, 128 were dengue seropositive cases, 2 of which were Malaria positive and 1 case was showed co-infection. We observed that hematological parameters like hemoglobin, platelet count, SGPT and total leucocyte count were significantly higher in both Dengue and Malaria. Conclusion:This study concluded that all patients presented with the febrile illness should be tested for both Malaria and Dengue. Both presented with similar clinical manifestations which is why specific diagnostic testing along with complete blood count is necessary to confirm the diagnosis and to know the severity of the illness.

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Section: Introductionmentioning

confidence: 99%

Distribution and burden of malaria and dengue infections in a tertiary care hospital

Sharma,

Bisht,

Jain

et al. 2024

Int. J. Mosq. Res.

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Frequency of pleural effusion in dengue patients by severity, age and imaging modality: a systematic review and meta-analysis

et al. 2023

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Background Identification of pleural effusion (PE) in dengue infection is an objective measure of plasma leakage and may predict disease progression. However, no studies have systematically assessed the frequency of PE in patients with dengue, and whether this differs across age and imaging modality. Methods We searched Pubmed, Embase Web of Science and Lilacs (period 1900–2021) for studies reporting on PE in dengue patients (hospitalized and outpatient). We defined PE as fluid in the thoracic cavity detected by any imaging test. The study was registered in PROSPERO (CRD42021228862). Complicated dengue was defined as hemorrhagic fever, dengue shock syndrome or severe dengue. Results The search identified 2,157 studies of which 85 studies were eligible for inclusion. The studies (n = 31 children, n = 10 adults, n = 44 mixed age) involved 12,800 patients (30% complicated dengue). The overall frequency of PE was 33% [95%CI: 29 to 37%] and the rate of PE increased significantly with disease severity (P = 0.001) such that in complicated vs. uncomplicated dengue the frequencies were 48% and 17% (P < 0.001). When assessing all studies, PE occurred significantly more often in children compared to adults (43% vs. 13%, P = 0.002) and lung ultrasound more frequently detected PE than conventional chest X-ray (P = 0.023). Conclusions We found that 1/3 of dengue patients presented with PE and the frequency increased with severity and younger age. Importantly, lung ultrasound demonstrated the highest rate of detection. Our findings suggest that PE is a relatively common finding in dengue and that bedside imaging tools, such as lung ultrasound, potentially may enhance detection.

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Discriminating malaria and dengue fever in endemic areas: Clinical, biochemical and radiological criteria

Cited by 2 publications

References 17 publications

Distribution and burden of malaria and dengue infections in a tertiary care hospital

Distribution and burden of malaria and dengue infections in a tertiary care hospital

Frequency of pleural effusion in dengue patients by severity, age and imaging modality: a systematic review and meta-analysis

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