Discriminating Interpatient Variabilities of RAS Gene Variants for Precision Detection of Thyroid Cancer
Guodong Fu,
Ronald S. Chazen,
Christina MacMillan
et al.
Abstract:ImportanceInterpatient variabilities in genomic variants may reflect differences in tumor statuses among individuals.ObjectivesTo delineate interpatient variabilities in RAS variants in thyroid tumors based on the fifth World Health Organization classification of thyroid neoplasms and assess their diagnostic significance in cancer detection among patients with thyroid nodules.Design, Setting, and ParticipantsThis prospective diagnostic study analyzed surgically resected thyroid tumors obtained from February 20… Show more
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