A 3 dimensional analogue of Sakai's theory concerning the relation between rational surfaces and discrete Painlevé equations is studied. For a family of rational varieties obtained by blow-ups at 8 points in general position in P 3 , we define its symmetry group using the inner product that is associated with the intersection numbers and show that the group is isomorphic to the Weyl group of type E (1) 7 . By normalizing the configuration space by means of elliptic curves, the action of the Weyl group and the dynamical system associated with a translation are explicitly described. As a result, it is found that the action of the Weyl group on P 3 preserves a one parameter family of quadratic surfaces and that it can therefore be reduced to the action on P 1 × P 1 .