As an important application of image encryption, digital medical image encryption plays an important role in the field of medical health and privacy protection. This paper put forwards a fully chaotic and strongly plaintext associated image encryption framework based on an improved chaotic system, block rotation and DNA computing. The algorithm generates multiple chaotic sequences by using different
one-dimensional seed chaotic maps under the sine transform framework for subsequent block rotation, DNA dynamic encoding and decoding, generating key images for DNA XOR calculation. Simulation experiments and comparative analysis have shown that
this algorithm can achieve fantastic encryption performance, resist various attacks, and have higher security levels and good generalization performance.