Discrepancies between leg-to-leg bioelectrical Impedance analysis and computerized tomography in abdominal visceral fat measurement

Lu, Hsueh-Kuan; Chen, Yu-Yawn; Yeh, Chinagwen; Chuang, Chih-Lin; Chiang, Li-Ming; Lai, Chung-Liang; Casebolt, Kevin M.; Lin, Wen-Long; Hsieh, Kuen-Chang

doi:10.1038/s41598-017-08991-y

Cited by 15 publications

(13 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gomez et al and Park et al reported bioimpedance analysis tends to underestimate VFA compared with CT [27–30]. Difference between VFA estimated by CT and BIA was large especially in the subjects with high BMI and large VFA estimated by CT [29, 30]. Our data with T2D patients are compatible to these previous studies.…”

Section: Discussionsupporting

confidence: 90%

Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes

Omura-Ohata

Son

Makino

et al. 2019

Cardiovasc Diabetol

View full text Add to dashboard Cite

BackgroundVisceral fat area (VFA) is a good surrogate marker of obesity-related disorders, such as hypertension, dyslipidemia and glucose intolerance. Although estimating the VFA by X-ray computed tomography (CT) is the primary index for visceral obesity, it is expensive and requires invasive radiation exposure. Dual bioelectrical impedance analysis (BIA) is a simple and reliable method to estimate VFA; however, the clinical usefulness of dual BIA remains unclear in patients with type 2 diabetes (T2D).MethodsWe estimated the VFAs by dual BIA and CT in 98 patients with T2D and assessed anthropometric parameters, blood test results, and the presence of comorbid hypertension and dyslipidemia. We compared the correlation between the VFAs examined by dual BIA and CT. Furthermore, we performed the receiver operating characteristic (ROC) analyses for the VFAs to detect the presence of comorbid hypertension and/or dyslipidemia with T2D, which are major comorbidities of visceral obesity, and estimated the area under the curve (AUC).ResultsThe measurement error between the VFAs by dual BIA and CT was significantly higher among patients with brain natriuretic peptide (BNP) ≥ 100 pg/mL than those with BNP < 100 pg/mL (39.2% ± 31.1% vs. 24.1% ± 18.6%, P < 0.05). After excluding patients with BNP ≥ 100 pg/mL, the VFA by dual BIA significantly correlated with the VFA by CT (r = 0.917; P < 0.0001). The AUC in the ROC analysis for the VFA by dual BIA to detect the presence of comorbid hypertension and/or dyslipidemia with T2D was almost equivalent to that for the VFA by CT.ConclusionsIn patients with T2D without elevated BNP > 100 pg/mL as indicator for fluid accumulation interfering with BIA, estimation of the VFA by dual BIA significantly correlated with that by CT and also detected comorbid hypertension and/or dyslipidemia with T2D equivalent to those detected by CT. Hence, dual BIA could be an alternative to CT as a standard method for estimating the VFA in patients with diabetes.

show abstract

Section: Discussionsupporting

confidence: 90%

Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes

Omura-Ohata

Son

Makino

et al. 2019

Cardiovasc Diabetol

View full text Add to dashboard Cite

show abstract

“…Four studies with a total of 186 participants compared agreement between ultrasound and MRI or CT to quantify IAAT thickness. Of the studies that estimated IAAT area, comparator methods included DXA and several BIA techniques . The BIA estimation of IAAT was based on unpublished equations derived from the instrument manufacturers.…”

Section: Resultsmentioning

confidence: 99%

Intra‐Abdominal Adipose Tissue Quantification by Alternative Versus Reference Methods: A Systematic Review and Meta‐Analysis

Murphy

Bacon

Morais

et al. 2019

Obesity

View full text Add to dashboard Cite

Objective: This meta-analysis aimed to assess the agreement between intra-abdominal adipose tissue (IAAT) quantified by alternative methods and the reference standards, computed tomography (CT) and magnetic resonance imaging (MRI). Methods: MEDLINE and EMBASE electronic databases were systematically searched to identify studies that quantified IAAT thickness, area, or volume by a comparator method and CT or MRI. Using an inverse variance weighted approach (random-effects model), the mean differences and 95% limits of agreement (LoA) were pooled between methods. Results: The meta-analysis included 24 studies using four comparator methods. The pooled mean differences were −0.3 cm (95% LoA: −3.4 to 3.2 cm; P = 0.400) for ultrasound and −11.6 cm 2 (95% LoA: −43.1 to 19.9 cm 2 ; P = 0.004) for bioelectrical impedance analysis. Dual-energy x-ray absorptiometry (DXA) quantified both IAAT area and volume with mean differences of 8.1 cm 2 (95% LoA: −98.9 to 115.1 cm 2 ; P = 0.061) and 10 cm 3 (95% LoA: −280 to 300 cm 3 ; P = 0.808), respectively. Conclusions: Ultrasound and DXA measure IAAT with minimal bias from CT or MRI, while bioelectrical impedance analysis systematically underestimates IAAT. However, with the exception of DXA for IAAT volume, the wide LoA caution against clinical or research use of the comparator methods and emphasize the need to optimize alternatives to the reference standards.

show abstract

“…Bioelectrical impedance analysis (BIA) is an alternative method for measuring body fat because it is fast, safe and non-invasive. 4,5,7,8 BIA showed a significant strong correlation with CT in measuring of VAT and SAT (r=0.89 and r=0.85, respectively) 6 and also with MRI in determining body fat and VAT (r=0.89 and r= 0.84, respectively). 9 Nitric oxide (NO) is a signaling and free radical molecule.…”

Section: Introductionmentioning

confidence: 85%

Body Fat Percentage, Waist Circumference and Body Mass Index are Correlated with Nitric Oxide Levels in Young Adults with Central Obesity

Nauli

Nurhasanah

Mahati

et al. 2021

Mol Cell Biomed Sci

View full text Add to dashboard Cite

Background: Central obesity stands for the corner-stone of cardio-metabolic health, while nitric oxide (NO) is a major regulator of cardiovascular function. To day, the correlation between serum NO metabolites nitrate/nitrite and the obesity components in young adults remains elusive. Thus, this current study was conducted to know the correlation between serum NO metabolites levels and body fat percentage, waist circumference (WC) as well as body mass index (BMI) in young adults with central obesity.Materials and Methods: A cross-sectional study was conducted in Riau, Indonesia, involving 79 young adults aged 18-25 years, composing of 39 and 40 subjects with and without central obesity, respectively. Anthropometric measurements were performed to assess WC and BMI. Body fat percentage was measured using bioelectrical impedance analysis and serum NO metabolites levels were assessed using Griess methods.Results: Levels of serum NO metabolites were significant higher in the subjects with central obesity (168.41±12.64 μmol/L) than that of normal subjects (70.57±44.99 μmol/L, p<0.001), but the levels were no significant different between male and female subjects. Serum NO metabolites levels were strongly correlated with total body fat (r=0.618, p<0.001), visceral fat (r=0.733, p<0.001), subcutaneous fat (r=0.547, p<0.001), WC (r=0.717, p<0.001) and BMI (r=0.788, p<0.001).Conclusions: For young adults in Riau, Indonesia, levels of serum NO metabolites are higher in the central obesity group than that of the normal. In this population, body fat percentage, waist circumference and body mass index are correlated with serum nitric oxide metabolites levels.Keywords: nitric oxide, body fat percentage, young adults, central obesity

show abstract

Discrepancies between leg-to-leg bioelectrical Impedance analysis and computerized tomography in abdominal visceral fat measurement

Cited by 15 publications

References 30 publications

Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes

Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes

Intra‐Abdominal Adipose Tissue Quantification by Alternative Versus Reference Methods: A Systematic Review and Meta‐Analysis

Body Fat Percentage, Waist Circumference and Body Mass Index are Correlated with Nitric Oxide Levels in Young Adults with Central Obesity

Contact Info

Product

Resources

About