Discrepancies between Intraoperative and Histological Evaluation of the Appendix in Acute Appendicitis

Bolmers, Matthijs D M; Jonge, Jeroen de; Rossem, Charles C. van; Geloven, A. A. W. van; Bemelman, Willem A.; Acker, Gijs Jd Van; Akkermans, B.; Akkersdijk, G. J. M.; Algie, G. D.; Allema, Jan Hein; Andeweg, Caroline S.; Appeldoorn, N.; Baal, J. G. van; Bakker, Chantal M. den; Bartels, Stephan; Berg, C. van den; Boekestijn, Bas; Boer, Frank C. den; Boerma, D.; Boom, Anne Loes van den; Boute, M. C.; Bouwense, Stefan; Bransen, Jeroen; Brussel, F. A. van; Busch, Olivier R.; Castro, Susana; Cense, H. A.; Croese, C.; Dalen, Thijs van; Dawson, I.; Dessel, Els Van; Dettmers, R.; Dhar, N.; Dohmen, F. Y.; Dongen, K. W. van; Duijvendijk, Peter van; Dulfer, R. R.; Dwars, Boudewijn J.; Eerenberg, J. P.; Elst, Maarten van der; Ende, E. van den; Fassaert, Leonie M.M.; Fikkers, J. T.; Foppen, J. W.; Furnee, E. J.; Garssen, F. P.; Gerhards, M. F.; Goor, Harry van; Graaf, J. S. de; Graat, Leon J.; Grootr, J.; Ham, Arie C. van der; Hamming, J. F.; Hamminga, J. T.; Harst, Erwin van der; Heemskerk, Jeroen; Heijne, Anders von; Heikens, Joost T.; Heineman, Erik; Hertogs, R.; Heurn, Ernst van; Hil, L. C. van den; Hooftwijk, A. G.; Hulsker, Caroline C. C.; Hunen, D. R.; Ibelings, M. S.; Klaase, Joost M.; Klicks, R.; Knaapen, L.; Kortekaas, R. T.; Kruyt, Flip M.; Kwant, S.; Lases, S. S.; Lettinga, T.; Loupatty, A.; Matthijsen, Robert A.; Minnee, Robert C.; Mirck, B.; Mitalas, Litza E.; Moes, Dirk Jan A R; Moorman, A. M.; Nieuwenhuijs, Vincent B.; Nieuwenhuizen, G. A.; Nijk, P. D.; Omloo, Jikke M.T.; Ottenhof, A. G.; Palamba, H.W.; Peet, Donald L. van der; Pereboom, Ilona T. A.; Plaisier, P. W.; Ploeg, A. P. van der; Raber, Marco; Reijen, M. M.; Rijna, Herman; Rosman, Camiel; Roumen, R.M.H.; Scmitz, R. F.; Velden, Arjan P. Schouten van der; Scheurs, W. H.; Sigterman, T. A.; Smeets, H.J.; Sonnevled, D. J.; Sosef, Meindert N.; Spoor, Simon; Stassen, Laurents P. S.; Steensel, Leendert van; Stortelder, E.; Straatman, Jennifer; Susante, H. J. van; Hoog, D. E. Suykerbuyk de; Scheltinga, Catharien Terwisscha van; Toorenvliet, Boudewijn R.; Verbeek, P. C. M.; Verseveld, M.; Volders, José H.; Vriens, Menno R.; Vriens, P.W.H.E.; Vrouenraets, B. C.; Wall, Bryan J. M. van de; Wegdam, Johannes A.; Westerduin, E.; Wever, Jan J.; Wijfels, N. A.; Wijnhoven, Bas P. L.; Winkel, Tamara A.; Zee, David C. van der; Zeillemaker, Anneke M.; Zietse, C.

doi:10.1007/s11605-019-04345-3

Cited by 9 publications

(12 citation statements)

References 22 publications

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“…The correlation rate of intra-operative finding with histopathological reports is debatable with a mentioned similarity of between 46.6% and 93.5% in different literatures. 40–44 …”

Section: Discussionmentioning

confidence: 99%

Pattern and Outcome of Acute Appendicitis: Observational Prospective Study from a Teaching Hospital, Addis Ababa, Ethiopia

Selassie

Ashebir

2021

OAEM

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Background Acute appendicitis is the most common cause of acute abdomen surgery. Despite its commonness and the abundance of literature on the subject, its diagnosis remains challenging. Delay in intervention results in complications of the process leading to increased morbidity and mortality. Methodology An observational prospective cohort study was conducted, and all patients who had undergone appendectomy for a clinical diagnosis of appendicitis were included in the study. Data were analysed using Statistical Package for Social Sciences (SPSS) version 23. Results Half of the study participants were in the age range of 18–25 years with male preponderance (63.9%). The mean duration of symptoms was 51.3 hours. The most common presenting symptom was abdominal pain (98.2%), while right lower quadrant tenderness was the most common sign (93.4%). Abdominal ultrasound was done in 81% of the study population with a sensitivity and specificity of 95.7% and 33.3%, respectively. Three-quarters (74.4%) of the patients had uncomplicated appendicitis, while 1.8% had a grossly normal appendix. None of the appendectomy specimens were sent for pathology. The mean hospital stay was 3.2 days. The morbidity and mortality rate were 3.8% and 0.4%, respectively. Conclusion Acute appendicitis was the most common emergency surgical procedure in the study period. Abdominal ultrasound was used in the majority of the patients as supplementary imaging for the diagnosis of acute appendicitis. Uncomplicated appendicitis took the major share of the intraoperative finding leading to acceptable morbidity and mortality rates.

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“…The correlation rate of intra-operative finding with histopathological reports is debatable with a mentioned similarity of between 46.6% and 93.5% in different literatures. 40–44 …”

Section: Discussionmentioning

confidence: 99%

Pattern and Outcome of Acute Appendicitis: Observational Prospective Study from a Teaching Hospital, Addis Ababa, Ethiopia

Selassie

Ashebir

2021

OAEM

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“… 8 , 9 , 10 , 11 For the macroscopic studies, in most of the available data, appendicular inflammation is classified as "normal", "inflamed", "phlegmone", "gangrenous", or "perforated", and therefore only the severity of the inflammation is taken into account but there are little descriptions in details. 12 , 13 , 14 , 15 , 16 , 17 For example, in the study of Pham et al, surgeons defined inflammations they saw, and pathology evaluations were compared with these macroscopic examinations. Eighty‐three percent of cases were compatible according to comparison of inflammation appearance in the specimen evaluation with the evaluation during surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Majority of the inflammations of appendectomy were described as in an ordinary range in the literature, and a standard course of the clinical process was occasionally defined 8‐11 . For the macroscopic studies, in most of the available data, appendicular inflammation is classified as "normal", "inflamed", "phlegmone", "gangrenous", or "perforated", and therefore only the severity of the inflammation is taken into account but there are little descriptions in details 12‐17 . For example, in the study of Pham et al, surgeons defined inflammations they saw, and pathology evaluations were compared with these macroscopic examinations.…”

Section: Discussionmentioning

confidence: 99%

Diagnosing granulomatous disease during appendectomy

Şenaylı

2021

Clinical Case Reports

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“…Se consideraron apendicitis aguda complicada aquellos casos en que se encontró necrosis (gangrena) o perforación del apéndice con o sin peritonitis local o generalizada durante la laparoscopía diagnóstica 12 . A su vez, se corroboró el diagnóstico de apendicitis complicada mediante la revisión del reporte de histopatología, en donde se confirmó la presencia de necrosis o perforación apendicular en la porción de la base del apéndice.…”

Section: Métodounclassified

Apendicectomía laparoscópica en pacientes con apendicitis aguda complicada con base apendicular comprometida: estudio de cohorte retrospectivo

Flores-Marín¹,

Rodríguez-Parra²,

Trejo-Ávila³

et al. 2021

CIRU

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Antecedentes: Los pacientes con base apendicular comprometida constituyen un subgrupo de pacientes con apendicitis complicada y existe poca información al respecto. Objetivo: Conocer la frecuencia de fístulas y fugas fecales en pacientes con apendicitis complicada con base apendicular comprometida. Método: Se trata de un estudio observacional, retrospectivo y transversal de pacientes operados de apendicectomía laparoscópica con base apendicular comprometida. Resultados: De 2015 a 2019 se encontraron 158 casos de apendicitis complicada, de los cuales 54 tenían la base apendicular comprometida. Hubo predominio de varones (66.7%) y la edad media fue de 38.7 años. En el 57.4% de los casos se realizó un nudo simple y en el 42.6% un punto transfictivo con invaginación del muñón. En relación con las complicaciones, el 16.7% desarrollaron abscesos intraabdominales, el 7.4% íleo y el 7.4% infección de herida. Hubo un paciente con fuga del muñón y un paciente con fístula cecal. El tiempo medio de estancia hospitalaria fue de 5.4 días (rango: 1-20). Se realizaron cinco reintervenciones: cuatro para drenaje de absceso intraabdominal y una por fuga del muñón. Conclusiones: En los pacientes con base apendicular comprometida, el manejo laparoscópico con ligadura simple o con punto transfictivo resulta en una baja frecuencia de fuga y fístula del muñón apendicular.

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Discrepancies between Intraoperative and Histological Evaluation of the Appendix in Acute Appendicitis

Cited by 9 publications

References 22 publications

Pattern and Outcome of Acute Appendicitis: Observational Prospective Study from a Teaching Hospital, Addis Ababa, Ethiopia

Pattern and Outcome of Acute Appendicitis: Observational Prospective Study from a Teaching Hospital, Addis Ababa, Ethiopia

Diagnosing granulomatous disease during appendectomy

Apendicectomía laparoscópica en pacientes con apendicitis aguda complicada con base apendicular comprometida: estudio de cohorte retrospectivo

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