Discovery of new tricyclic spiroindole derivatives as potent P-glycoprotein inhibitors for reversing multidrug resistance enabled by a synthetic methodology-based library
Tao Yu,
Rong Zeng,
Yu Guan
et al.
Abstract:Based on synthetic methodology-based library, a new class of tricyclic spiroindole derivatives as potent P-glycoprotein inhibitors with excellent tumor multidrug resistance reversal activity was discovered.
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