Discovery of new pesticide candidates from nature: design, synthesis and bioactivity research of rutaecarpine derivatives
Miao‐miao Chen,
Xin Guo,
Tai‐qing Li
et al.
Abstract:BACKGROUNDThe invasion of viruses and fungi can cause pathological changes in the normal growth of plants and is an important factor in causing plant infectious diseases. These pathogenic microorganisms can also secrete toxic metabolites, affecting crop quality and posing a threat to human health. In this work, we selected the natural product rutaecarpine as the lead compound to achieve the total synthesis and structural derivation. The antiphytoviral activities of these compounds were systematically studied u… Show more
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