“…The group of non-steroidal 11β-HSD1 inhibitors includes, inter alia, 4-substituted 2-aminothiazole derivatives: Biovitrum BVT-2733, Biovitrum BVT-14225 and Biovitrum BVT-3498 [ 24 , 25 , 26 , 27 ] and highly selective 2-aminothiazol-4(5 H )-es: Amgen 2922 and AMG-221 (BVT-83370) [ 24 , 28 , 29 , 30 ]. In the case of the 11β-HSD2 isoform, the CBX diastereoisomer (18α-glycyrrhetinic acid 3β- O -hemisuccinate, αCBX) is an effective inhibitor [ 31 ], whereas, among the non-steroidal inhibitors, antifungal drugs: itraconazole and posaconazole, which are the triazole derivatives, can be mentioned Scheme 2 ) [ 32 ].…”