Discovery of circulating miRNAs as biomarkers of chronic Chagas heart disease via a small RNA-Seq approach
Silvina R. Villar,
Alfonso Herreros-Cabello,
Francisco Callejas-Hernández
et al.
Abstract:Chagas disease affects approximately 7 million people worldwide in Latin America and is a neglected tropical disease. Twenty to thirty percent of chronically infected patients develop chronic Chagas cardiomyopathy decades after acute infection. Identifying biomarkers of Chagas disease progression is necessary to develop better therapeutic and preventive strategies. Circulating microRNAs are increasingly reliable biomarkers of disease and therapeutic targets. To identify new circulating microRNAs for Chagas dis… Show more
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